Drp1 inhibition amelioratesα-synuclein-mediated neurodegeneration in rats
Objective: To provide new insights on the relationships occurring between mitochondria physiology and α-synuclein (α-syn) accumulation in an animal model of progressive neurodegeneration. Background: In…Is the assessment of 5 meters of gait with body-worn-sensors enough to recognize Parkinsonian gait?
Objective: To classify step-by-step gait patterns of Parkinson's disease (PD) patients and older adults from the assessment of short episodes of gait with body-worn-sensors (BFS)…α-synuclein CSF levels correlate with urinary dysfunction in early de novo Parkinson’s disease patients
Objective: To explore the association between levels of α-synuclein burden and urinary dysfunction in early de novo (untreated) Parkinson's disease (PD) patients. Background: Urinary dysfunction…Sodium butyrate attenuates rotenone-induced neurodegeneration via enhancing autophagy and preventing α-synuclein aggregation
Objective: To investigate whether sodium butyrate (NaB) could enhance autophagy and thus exert a neuroprotective effect through the modulation of α-synuclein in animal models of…Lrrk2 alleles modify host response to microbial infections
Objective: The mechanisms by which allelic changes in LRRK2 modulate the susceptibility to Parkinson's disease, Crohn's disease and leprosy remain unknown. We hypothesized that leucine-rich…Analysis of LINGO1 and LINGO2 genes in essential tremor and Parkinson’s disease
Objective: We studied the involvement of LINGO1 and LINGO2 in Russian patients with ET and PD. Background: Genetics of ET is unclear. Three candidate loci…Resting-state functional connectivity of subthalamic nucleus in different phenotypes of Parkinson’s disease
Objective: To explore the different resting-state functional connectivity of subthalamic nucleus (STN) in different phenotypes of Parkinson's disease (PD). Background: The STN is one of…The relationship between cognitive task and postural stability in the early stages of Parkinson’s disease
Objective: To examine the presence of dual task interference with cognitive tasks on postural stability in the early stages of Parkinson's disease (PD). Background: There…Parkinson’s disease-linked mutation in DNAJC13 causes specific trafficking defect in endosomal pathway
Objective: The aim of this study is to investigate the effect of mutant DNAJC13 on the vesicle transport machinery using cultured cellular model. Background: Recently,…Combined effects of visual and auditory cues on gait initiation in Parkinson’s disease
Objective: To investigate the combined effects of visual and auditory cues on gait initiation and to investigate the correlation between the clinical rates of gait…
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