Effect of Venglustat by GBA Mutation Severity in Patients With Parkinson’s Disease
Objective: Report outcomes from Part 2 of the phase 2 MOVES-PD trial (NCT02906020) in patients with PD stratified by glucocerebrosidase (GBA) gene mutation severity. Background:…Causes of deaths in patients with Parkinson’s disease in the era before the use of modern drug therapy and at the present time
Objective: to study the impact of modern pharmacotherapy of Parkinson's disease (PD) on the main causes of death. Background: the modern era of the use…Hemiparkinsonism Due to Diencephalic Lesion with 24 Years of Levodopa Response and Only Mild Dyskinesia
Objective: To present a case of a long-standing hemiparkinsonism due to cerebral lesion with a continuous response to a stable dose of levodopa with only…A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson’s disease
Objective: To report the identification of a novel variant in the gene encoding alpha-synuclein (SNCA), segregating with Parkinson’s Disease (PD) in two families of Turkish…Neurofilament light is related to fractional anisotropy in early Parkinson’s diesease
Objective: We aimed to determine whether plasma NfL reflects changes in brain white matter integrity as measured using fractional anisotropy (FA) in patients with early…Apathy: an underestimated feature in premotor period of GBA and LRRK2 non-manifesting mutation carriers.
Objective: The aim was to detect the differences between GBA and LRRK2 mutation carriers without Parkinson’s disease and healthy controls (HC) on neuropsychiatric symptoms. Background:…Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI): Studies Preceding Clinical Validation
Objective: Summarize the findings from 3 developmental studies of the Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI) – a novel endpoint for assessing PD symptoms.…Determining the content of a clinician-rated tool for freezing of gait severity
Objective: This study aimed to determine clinician’s ratings of the most important triggering circumstances to be examined and aspects of freezing of gait (FOG) to…An International Pre-Implementation Survey To Assess The Acceptability Of Telemedicine As An Alternative To In-Person Clinic Consultations For PD
Objective: To assess the acceptability of virtual consultations as an option for out-patient clinic consultations for PD Background: The practice of telemedicine increased dramatically on…Single-Trajectory Multiple-Target Deep Brain Stimulation to treat Mobility and Cognition in Parkinson’s Disease: a Double-Blind, Randomized, Cross-Over Pilot Study
Objective: To assess the benefit of deep brain stimulation (DBS) to improve cognition in Parkinson’s Disease (PD). Background: Patients with advanced PD suffer from both…
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