Pain syndrome in Parkinson’s disease: neurophysiological and MRI morphometric features
Objective: Investigation of the neurophysiological disorders and identify their structural correlates in the brain by MRI studies with using voxel-based morphometry to reveal subtle changes…Does constipation predict cognitive impairment and dementia in de novo Parkinson’s disease patients? A multi-cohort longitudinal data analysis
Objective: To investigate if constipation predicts the development of cognitive impairment (CI) and dementia in de novo Parkinson’s disease (PD). Background: Constipation is one of…Effects of Sleep Disorders on the Quality of Life in Parkinson’s Disease: A Study of 84 Ibadan Patients
Objective: To assess the effects of sleep disorders on the quality of life in PD patients. Background: Parkinson’s disease is a progressive neurodegenerative disease. The…Urinary Symptoms and Parkinson’s Disease: The Patient’s Perspective
Objective: To learn about prevalence rates and the impact of urinary symptoms on day-to-day function and quality of life from the patient’s perspective. Background: Urinary…Dietary and Plasma Polyunsaturated Fatty Acids in Parkinson’s Disease
Objective: We assessed the dietary intakes and plasma levels of polyunsaturated fatty acid (PUFA) in Parkinson's disease (PD), and their relation to motor and non-motor…Donepezil for mild cognitive impairment in Parkinson’s disease: A 48-week follow-up study
Objective: To investigate the efficacy of donepezil for mild cognitive impairment (MCI) in Parkinson’s disease (PD). Background: MCI is common in PD. The mechanism of…Safety, Tolerability, and Pharmacodynamic Profile of DNL201 at dose levels demonstrating LRRK2 inhibition in Parkinson’s Disease Patients with and without LRRK2 mutations
Objective: To evaluate safety, tolerability, and target engagement of DNL201, a LRRK2 inhibitor, in Parkinson’s disease (PD) patients. Background: Mutations in LRRK2 impact both familial…Rapid on-time onset and sustained improvements in motor states throughout the day following treatment with levodopa/carbidopa intestinal gel (LCIG) vs immediate-release levodopa/carbidopa oral capsules (LCIR)
Objective: To assess the speed of on-time onset and characterize the patterns of motor states throughout the day in advanced Parkinson’s disease patients treated with…A Discrete-Choice Experiment Evaluating Preferences for On-Demand Treatments for Patients with Parkinson’s Disease and “OFF” Episodes
Objective: To quantify patient preferences for on-demand treatments among patients with Parkinson’s disease (PD) and “OFF” episodes. Background: Patients with PD develop potentially disabling “OFF”…Euphoria-inducing lead contacts: mapping of image and electrophysiology in Parkinson’s disease
Objective: We characterized stimulation-induced euphoria during the programming of STN DBS. The lead contacts where euphoria was elicited were characterized anatomically and electrophysiologically. Background: Mood…
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