Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI): Studies Preceding Clinical Validation
Objective: Summarize the findings from 3 developmental studies of the Parkinson’s Disease Functional Impacts Digital Instrument (PD-FIDI) – a novel endpoint for assessing PD symptoms.…Determining the content of a clinician-rated tool for freezing of gait severity
Objective: This study aimed to determine clinician’s ratings of the most important triggering circumstances to be examined and aspects of freezing of gait (FOG) to…An International Pre-Implementation Survey To Assess The Acceptability Of Telemedicine As An Alternative To In-Person Clinic Consultations For PD
Objective: To assess the acceptability of virtual consultations as an option for out-patient clinic consultations for PD Background: The practice of telemedicine increased dramatically on…Single-Trajectory Multiple-Target Deep Brain Stimulation to treat Mobility and Cognition in Parkinson’s Disease: a Double-Blind, Randomized, Cross-Over Pilot Study
Objective: To assess the benefit of deep brain stimulation (DBS) to improve cognition in Parkinson’s Disease (PD). Background: Patients with advanced PD suffer from both…Limitations of conventional dopaminergic medication in advanced Parkinson’s disease: results from 127 patients treated with Levodopa Carbidopa Intestinal Gel
Objective: To evaluate the characteristics of the last conventional dopaminergic treatments in a large cohort of patients with advanced Parkinson’s Disease (APD) treated with Levodopa…MAPT mutation frontotemporal dementia with parkinsonism: when previous results can skew the diagnosis
Objective: Case report presentation. Background: In frontotemporal dementia with parkinsonism (FTDP), several mutations in MAPT gene have been identified, and numerous family cases were reported,…α-Synuclein in sympathetic nerve fibers distinguishes PRKN from LRRK2 and other genetic forms of Parkinson’s Disease
Objective: This cross-sectional observational study compared magnitudes of intra-neuronal deposition of α-synuclein in common and rare genetic forms of Parkinson’s disease. Background: Cytoplasmic inclusions of…Distinct cholinergic reactivity to dopamine is related with differed parkinsonian tremor responsiveness
Objective: We aimed at exploring the mechanisms of differed tremor responsiveness to dopamine through investigating the cholinergic and dopaminergic reactivity during dopamine administration in PD.…Clinical profile and treatment outcomes of inherited hypermanganesemia among 27 Indian children: A retrospective multi-centric study
Objective: To describe clinical, laboratory features and treatment outcomes among children with IH-Mn Background: Inherited hypermanganesemia (IH-Mn) is a recently described neurogenetic condition caused by mutations…A Computer-Vision Based Method for Quantifying Parkinsonian Gait
Objective: We proposed and evaluated a novel approach for estimating severity of gait impairment in Parkinson’s disease using a computer vision-based methodology. Background: Gait is…
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