The Clinical and Biological effects of a Whole Foods and Plant-Based Dietary Intervention in Parkinson’s Disease
Objective: The Plants for Parkinson trial aims to investigate whether prolonged adherence to a plant-based and whole foods-derived dietary pattern can alleviate motor- and gastrointestinal…When Surgical Candidates Become Ineligible: Loss of Deep Brain Stimulation Eligibility in Parkinson’s Disease — A Descriptive Study from a Brazilian Referral Center
Objective: To describe the clinical and non-clinical reasons leading to loss of surgical eligibility among patients initially considered candidates for Deep Brain Stimulation (DBS) in…Impact of Symptom-Specific Odorants on the Diagnostic Accuracy of Brief Olfactory Tests in Parkinson’s Disease
Objective: To evaluate whether the addition of PD symptom-specific odorants improves diagnostic accuracy in distinguishing patients with PD from healthy controls. Background: Parkinson’s disease (PD)…About Data Missingness in Wearable Monitoring of Parkinson’s Disease
Objective: To examine how adherence and data completeness vary throughout the day in wearable monitoring of people with Parkinson’s disease (PwPD), and whether missing data patterns are associated with disease severity. Background: Wearable devices…Improved “Good On” Time and Reduced Motor Fluctuations After Switching to IPX203: Interim Real-World Results from the First 111 Patients in ELEVATE PD
Objective: Evaluate interim outcomes from the real-world study of IPX203, assessing its impact to extend “Good On” time and reduce “Off” time in PD patients…LFP-Based Deep Brain Stimulation Programming and Transition to Adaptive Deep Brain Stimulation in a Patient with Parkinson’s Disease: A Case Report from Thailand
Objective: This case report represents one of the first practical implementations of LFP-guided programming and adaptive DBS in Thailand. Background: Deep brain stimulation (DBS) of…DBS Evoked Cortical Potentials Can Predict Tremor Suppression
Objective: To relate the DBS evoked cortical potential (ECP) P25 to the suppression of tremor. Background: DBS‑ECPs have been investigated in DBS of the subthalamic…Diagnostic Validity of PD Identification in a Neurologist-Certified National Drug Reimbursement Registry
Objective: To evaluate the diagnostic validity of PD identification in a national drug reimbursement registry requiring neurologist-confirmed diagnoses. Background: Administrative healthcare databases are widely used…Assessing The Role Of Afg3l2 Pathogenic Variants In Parkinson’s Disease
Objective: The aim of this study is to investigate the potential link between AFG3L2 rare pathogenic/likely pathogenic variants with Parkinson’s disease (PD). Background: AFG3L2 is…Deciphering the NLRP3-Driven Olfactory–Brain Axis in Parkinson’s disease: Neuroprotective Role of Betulin
Objective: The present study aimed to elucidate the molecular mechanism underlying bidirectional olfactory–brain dysfunction mediated through NLRP3 inflammasome activation in cellular models of PD and…
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