Neuroprotective Effects of Curcumin on Hippocampal-PPN Circuitry in a Rotenone-Induced Rat Model of Parkinson’s Disease
Objective: This study investigated the neuroprotective effects of curcumin on the hippocampal-pedunculopontine nucleus (PPN) axis in a rotenone-induced rat model of PD. Background: Parkinson’s disease…Video-Nystagmographic Biomarkers of Oculomotor Dysfunction in Parkinson’s Disease: Correlation With Motor Severity and Cognition
Objective: To quantitatively evaluate oculomotor dysfunction using video-nystagmography (VNG) in patients with Parkinson’s disease (PD) and determine its association with motor severity, disease duration, and…Multidisciplinary Care Preserves Function and Quality of Life After Nursing Home Placement in Late-Stage Parkinson’s Disease: A Prospective Cohort Study
Objective: To assess whether multidisciplinary care following the time of nursing home placement for patients with Parkinson's disease (PD) can maintain their activities of daily…Multimodal Deep Learning for Parkinson’s Disease Screening: Fusing Quantitative Gait Analysis and Clinical Features
Objective: To develop and validate a machine learning model integrating quantitative gait parameters and clinical features to enhance the diagnostic accuracy of Parkinson's disease (PD)…Subthalamic Nucleus Oscillatory Coupling During Sleep is Impaired in Parkinson’s Disease and Associated with Memory Consolidation
Objective: To investigate whether the subthalamic nucleus (STN) supports sleep-dependent memory consolidation through hierarchical oscillatory coupling, and whether this mechanism is disrupted in Parkinson's disease…Longitudinal cognitive trajectories and predictors of dementia conversion in Parkinson’s disease
Objective: To determine clinical predictors of longitudinal cognitive decline and dementia conversion in a real-world Parkinson’s disease (PD) cohort. Background: Cognitive impairment is one of…Device-aided Therapies are Associated with Significantly Greater Improvement in Quality of Life in Younger Patients Earlier Within Advanced Parkinson’s Disease
Objective: To evaluate the impact on health-related quality of life (HRQoL) of treatment with device-aided therapies (DAT) in younger patients earlier within advanced Parkinson's disease…Attention-Enhanced Deep Learning for Midbrain MRI Segmentation in Parkinson’s Disease
Objective: To develop an automated deep learning framework for robust midbrain segmentation in MRI data of Parkinson’s disease patients. Background: Structural alterations in the midbrain…Characteristics And Progression Of Non-Motor Symptoms In Parkinsons Disease
Objective: The aim of this study is to investigate the characteristics and the progression of different domains of NMS in PD, and to determine their…Item – Level Drivers of Certification Failure in the MDS-UPDRS Motor Examination: A Five-Year Global Analysis
Objective: To identify individual Part III items that disproportionately contribute to first-attempt certification failure and to evaluate the stability of these patterns over five years.…
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