Orthostatic Hypotension is Associated with Worse Verbal Letter Fluency and Lower Neural Efficiency While Upright in Parkinson’s Disease: A Pilot Study
Objective: To evaluate positional effects on cognitive performance and cerebral hemodynamics in Parkinson’s disease (PD) patients with and without orthostatic hypotension (OH). Background: OH is…Apathy produces selective deficits in cognitive function when controlling for depression in patients with Parkinson’s disease
Objective: To compare differences in the mean cognitive impairment (CI) of patients with and without clinically significant apathy in PD, PD-mild cognitive impairment (PD-MCI), and…Integrating Non-Motor Symptoms and Gender Variability in Machine Learning for Early Parkinson’s Disease Detection
Objective: Our study aimed to develop a machine learning (ML) model for the early detection of Parkinson's disease (PD), utilizing non-motor symptoms (NMS) and DNA…Prevalence and characteristics of anxiety in Parkinson’s disease
Objective: To evaluate the characteristics of anxiety in relation to motor and non-motor symptoms in a cohort of PD patients. Background: Anxiety is a frequent…When Off Can Cost Life: Myocardial Infarction Due to Spontaneous Coronary Dissection as a Catastrophic Manifestation in Advanced Parkinson’s Disease.
Objective: Describe a patient with PD who suffered an acute myocardial infarction during a severe OFF period. Background: Advanced PD is characterized by complications including…Uncovering Non-Motor Subtypes in Parkinson’s Disease through Machine Learning
Objective: This study aims to uncover subtypes of Parkinson’s disease (PD) through unsupervised machine learning (ML), based on the predicted evolution of non-motor symptoms (NMS).…Detecting impulsivity through speech in patients with Parkinson’s Disease: A principle proof study
Objective: To identify speech biomarkers to assess impulsivity in patients with Parkinson's disease (PwPD). Background: Although PD mainly presents with motor symptoms, the burden of…Neurophysiological Underpinnings of Apathy in Parkinson’s Disease Versus Depressive Disorders: A Comparative Study
Objective: The manifestation of apathy in neurological and psychiatric conditions such as Parkinson's Disease (PD) and depressive disorders presents a significant clinical challenge. This study…PREVENT-PD: A Framework for Collecting Trichloroethylene Contamination Data in New York State
Objective: To describe methodology used to collect data on trichloroethylene (TCE) and perchloroethylene (PCE) contamination in Monroe County, New York. Background: TCE and PCE, chlorinated…Clinical profile of early-onset Parkinson’s disease
Objective: Describe motor and non-motor symptoms, complications and treatment in patients with early-onset Parkinson's disease (EOPD) Background: PD usually affecting people over age 60, clinically…
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