Nutritional Status as a Modifiable Determinant of Clinical Outcomes in Parkinson’s Disease: A 12-Month Longitudinal Study in Patients Treated with DBS and L-Dopa
Objective: To analyze longitudinal changes in nutritional status in Parkinson’s disease (PD) patients treated with deep brain stimulation (DBS), compared with pharmacological therapy (L-dopa) and to…Visualization of Small Brainstem Nuclei With the Ultra-High Performance NeuroEXPLORER PET Camera: a Comparison Study Using 18F-AV133
Objective: To compare the performance of 18F-AV133 between NeuroEXPLORER (NX) and standard resolution Siemens Biography (mCT) positron emission tomography (PET) cameras in people with Parkinson's…Early Complement Activation Prunes Inhibitory Synapses in Prodromal Synucleinopathy Independent from Lewy Pathology.
Objective: To identify early molecular and cellular changes associated with dopaminergic neuron vulnerability and synuclein pathology across different disease contexts. Background: Parkinson’s disease (PD) is…Temporal Ordering of Biomarker Abnormality Events Leading to Cognitive Impairment in Parkinson’s Disease: A Disease Event-Based Model Analysis of the PPMI Cohort
Objective: To estimate the temporal ordering of multimodal biomarker abnormality events leading to cognitive impairment in PD using a Disease Event-Based Model (DEBM), incorporating clinical,…Dietary and Environmental Risk factors of Parkinson’s Disease: An integrated study combining Network Pharmacology and Molecular Docking Analyses
Objective: This large-scale case-control study using network pharmacology and molecular docking, aimed to identify dietary and environmental risk factors of Parkinson’s disease (PD). Background: PD…Towards automated deep brain stimulation programming using neurophysiology and artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…Wearable-based Virtual Motor Exam enables remote tracking of motor symptom progression in early-stage Parkinson’s disease
Objective: To evaluate the ability of smartwatch-based measures of tremor, bradykinesia and gait to capture Parkinson’s disease (PD) progression. Background: Wearable sensors enable remote, objective,…Effectiveness of Interactive Rhythmic Stimulation on Gait Improvement in Elderly Patients: An R and Python Perspective
Objective: To evaluate the effectiveness of interactive rhythmic stimulation on gait improvement in elderly patients using data-driven insights from R and Python-based analyses. Background: Gait…Case report and Literature Review on Atypical Parkinson’s Disease
Objective: Atypical parkinsonism is classified as a subgroup of Progressive neurodegenerative diseases, characterized by symptoms of Parkinson's disease. Background: Progressive supra nuclear palsy of the…Empathy in Action A Sensory Experience for Healthcare Providers
Objective: Evaluate the impact of a multisensory, hands-on experience designed to simulate the motor and non-motor symptoms of Parkinson’s disease (PD) on healthcare providers’ (HCPs)…
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