Timing And Type Of Adverse Events Following Long-Term Treatment With Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) Infusion – Data From The ELEGANCE Interim Analysis
Objective: To evaluate the type and timing of occurrence of treatment-emergent adverse events (AEs) in people with advanced Parkinson’s disease (PD) following up to one…Transcranial Direct Current Stimulation (tDCS) to Enhance Cognitive Function in Parkinson’s Disease: A Systematic Review and Meta-analysis with Implications for African Healthcare
Objective: This study assesses the efficacy of transcranial direct current stimulation (tDCS) in improving cognitive function in Parkinson’s disease (PD) patients and explores its relevance…Predicting Parkinson’s disease severity and cognitive decline using blood-based ferroptotic biomarkers
Objective: As Parkinson’s disease progresses, patients require second-line treatments such as subthalamic stimulation, the benefits of which may be undermined by the appearance of non-dopaminergic…Biomarker Panels for Parkinson’s Disease using Multi-Omics Approach: Recent Developments and Future Directions
Objective: The main objective is to identify potential biomarker panels that may represent disease onset, progression, and risk factors for Parkinson's disease (PD). Background: PD…Parkinson’s Disease and Type 2 Diabetes Severity: a Case-control Biomarker Study
Objective: We used blood-based markers of neuroaxonal damage, inflammation, and glycaemic control to examine whether Type 2 Diabetes (T2D) is linked to a more severe…Color Vision In Patients With Clinical Manifestations Of Rem Sleep Behavior Disorder
Objective: To evaluate the presence of changes in color vision in patients with REM sleep behavior disorder (RBD), Parkinson's disease (PD), and controls. Background: Visual…CSF Cadaverine and Other Polyamines as Biomarkers of Parkinson’s Disease: A PPMI Metabolomics Analysis
Objective: To identify novel biomarkers of Parkinson’s disease (PD) in Parkinson's Progression Markers Initiative (PPMI) cerebrospinal fluid (CSF) samples. Background: Altered polyamine levels in plasma…Immune cell changes in early Dementia with Lewy Bodies
Objective: To examine if immune cell changes are present in early stages of Dementia with Lewy Bodies (DLB). Background: Evidence for inflammation in synucleinopathies has…Reliability and Validity of In-home Tele-Neuropsychological Testing in Patients with Parkinson’s Disease: A Randomized Trial
Objective: To assess the reliability and diagnostic validity of in-home tele-neuropsychological testing (in-home tele-npt) in individuals with Parkinson’s disease (PD). Background: Neuropsychological testing is inaccessible…Baseline cerebrospinal levels of p-tau and amyloid beta and striatal dopamine transporter binding predict mild cognitive impairment and dementia diagnosis in Parkinson’s disease
Objective: To assess whether baseline measurements of neuroimaging and biofluid-based biomarkers predict diagnosis of mild cognitive impairment (MCI) and dementia at 5-year follow-up in early…
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