Initial clinical experience with levodopa-entacapone-carbidopa intestinal gel infusion (LECIG) for the management of advanced Parkinson´s disease in Croatia
Objective: To report preliminary results of a 12-week, prospective, multicenter, observational study of the efficacy and safety of LECIG for the treatment of advanced Parkinson´s…Genome-wide association identifies novel etiological insights associated with Parkinson’s Disease in African and African admixed populations
Objective: To provide a genome-wide association study (GWAS)- based insight into the genetics of Parkinson’s disease (PD) in Africans and African admixed populations. Background: Understanding…Early onset of efficacy during titration in US phase 3 open-label InfusON trial of apomorphine subcutaneous infusion for Parkinson’s disease motor fluctuations
Objective: Evaluate safety/onset of efficacy during titration of continuous subcutaneous apomorphine infusion (CSAI) for motor fluctuations in U.S. outpatients with Parkinson’s disease (PD). Background: Global…Clinical Improvement and drastic reduction of Equivalent Dose of Levodopa (LEDD) in an Advanced Parkinson’s Disease Patient after Levodopa/Entacapone/Carbidopa Intestinal Gel (LECIG) Treatment
Objective: Describe a patient in which after starting continuous infusion of LECIG a large reduction of the LEDD is achieved. Background: Gastroparesis (GP) is one…Trajectories of Physical Performance in Prodromal and Early Parkinson’s Disease
Objective: To describe trajectories of physical performance in prodromal and early Parkinson’s Disease (PD). Background: There is a need to better characterize the prodromal and…First approach of a sensor-based assessment of the camptocormia angle
Objective: To implement inertial-measurement-unit (IMU) sensors as a reliable and valid diagnostic tool in assessing the camptocormia angle (CA). Background: Camptocormia is a pathological non-fixed…Preoperative trajectory planning is important to minimize intracerebral hemorrhage after deep brain stimulation, in comparison with ventricle peritoneal shunt.
Objective: We compared the occurrence of postoperative intracerebral hemorrhage (ICH) in deep brain stimulation (DBS) and ventricle peritoneal (VP) shunt at our institution. Background: Although…Analysis of α-Synuclein Seed Amplification Assay in Carriers of GBA and LRRK2 Pathogenic Variants
Objective: To assess α-synuclein seed amplification assay (αS-SAA) in cerebrospinal fluid (CSF) from a cohort of PD patients and non-manifesting carriers (NMCs) of pathogenic GBA…Initial 24-hours Levodopa Carbidopa Intestinal Gel initiation in advanced Parkinson’s disease
Objective: To evaluate the profile of those patients with advanced Parkinson’s Disease (APD) in which we decided to use continuous 24-hour administration of Levodopa Carbidopa…Ocular microtremor in Parkinson’s Disease: Protocol for an observational pilot study
Objective: This study aims to examine OMT in people with PD (PwPD) compared to healthy older adults. Identifying OMT as a PD biomarker could better…
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