Testing the applicability of the dysarthria analyzer to detect levodopa effects on speech in a German cohort of people with Parkinson’s disease
Objective: To test the applicability of “the dysarthria analyzer” in a levodopa challenge test to determine short term effects of levodopa on acoustic speech parameters.…Reliability and validity of automatedly generated vowel space metrics as biomarkers of articulatory impairment severity and progression in early Parkinson’s Disease
Objective: To evaluate the reliability and validity of automatedly generated vowel space metrics from remotely collected smartphone speech samples as biomarkers of articulatory impairment severity…Incremental Hospitalizations and Associated Costs of Co-existing Dementia in Patients with Parkinson’s Disease Psychosis: An analysis of US Medicare Beneficiaries
Objective: To evaluate incremental hospitalizations and costs among Medicare patients with Parkinson's disease psychosis (PDP) vs. PDP+dementia (PDP+D). Background: Research examining hospitalizations and costs of…Isolation of L1CAM-extracellular vesicles reveals signs of insulin resistance in Parkinson’s disease
Objective: The aim of this study was to test the utility of isolating L1 Cell Adhesion Molecule (L1CAM)-derived extracellular vesicles (EVs) in quantification of glucose…Combined effect of polygenic background and GBA Pathogenic variants in Parkinson’s disease risk
Objective: We aimed to investigate whether polygenic background affects the penetrance of Parkinson’s disease (PD) among carriers of heterozygous pathogenic variants (PV) in GBA. Background: Several rare homozygous mutations within…Potential role of Alpha-synuclein levels in Platelets in GBA-related PD
Objective: Identification of a blood biomarker to predict PD diagnosis or to monitor the disease progression. Background: Previous evidence suggests differences in systemic alpha-synuclein levels…Neuropsychological and quality of life outcome comparison after awake and asleep pallidal deep brain stimulation (DBS) surgery for Parkinson’s disease
Objective: To compare cognitive, psychiatric and quality of life (QoL) outcomes after awake and asleep bilateral pallidal (GPi) deep brain stimulation (DBS). Background: Prior studies…Dopamine depletion of striatal subregions and motor dysfunction in prodromal and clinical Parkinson’s disease
Objective: This aim of this study was to investigate how dopamine depletion of different striatal subregions contributes to motor symptoms in patients with prodromal and…REM sleep behaviour disorder in Parkinson’s disease: prevalence and correlation with other sleep parameters
Objective: to assess the prevalence of probable rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson’s disease (PD) patients and its correlation with other…Vagus nerve degeneration in Parkinson’s disease: correlation with autonomic symptoms and pupillography
Objective: To test the hypothesis that vagus nerve (VN) atrophy is pronounced in the body-first subtype of Parkinson’s disease (PD) and coincides with pupillary dysfunction.…
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