Dysphagia and dopaminergic neurodegeneration in Parkinson’s Disease
Objective: To evaluate the association between dysphagia and neurodegeneration of the putaminal dopaminergic system in people with early-stage treated with symptomatic therapy and advanced-stage Parkinson’s…Correlation of Functional Motor Assessments Used at Parkinson’s disease by Physiotherapists in Clinical Practice
Objective: The aim of this study was to verify whether there is a correlation between UPDRS motor score and non-specific assessments for PD commonly used…Caffeine Intake Interacts with Gene Variants in Parkinson’s disease
Objective: We investigate interactions of caffeine intake with PD risk variants and determine PD risk estimates in caffeine-drinkers carrying these variants. Background: Caffeine intake reduces…Impact of istradefylline on the onset of dyskinesia in Parkinson’s Disease patients with wearing off: a randomized controlled study (ODYSSEI)
Objective: To determine the effect of long-term treatment with istradefylline (IST) on the time to onset of dyskinesia in Parkinson’s disease (PD) patients with wearing-off…Imaging the noradrenergic system in Parkinson’s disease: A [11C]Yohimbine PET and neuromelanin MRI study
Objective: To assess two aspects of the noradrenergic system using multimodal in vivo imaging in a sample of Parkinson’s disease (PD) patients and healthy controls…Clinical severity in Parkinson’s disease is determined by decline in cortical compensation
Objective: We tested whether inter- and intra-individual differences in clinical severity are determined by cortical compensation, and not just by basal ganglia dysfunction. Background: Motor…Turning 360 degrees in standing – associations with perceived walking difficulties and comfortable gait speed in people with drug naïve/early Parkinson’s disease.
Objective: To investigate how turning performance (360 degrees in standing) is associated with perceived walking difficulties and comfortable gait speed in people with drug naïve…Comparision of objective Parkinson’s disease monitoring systems and the interpretations of results
Objective: To examine the agreeement between two objective Parkinson’s disease (PD) monitoring systems (PKG and STAT-ON) and clinical information from a resident physician’s interview or…Identifying neural biomarkers of motivated behavior in Parkinson’s disease using sensing-capable DBS devices
Objective: To investigate neural correlates of motivated, goal directed behavior within the basal ganglia. Background: Apathy is a common and debilitating complication of Parkinson’s disease…Longitudinal changes in brain networks associated with clinical symptoms in idiopathic rapid eye movement sleep behavior disorder
Objective: We aimed to assess changes in brain functional networks and accompanying symptoms over years in patients with idiopathic rapid eye movement sleep behavior disorder…
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