Wearable sensors and AI in Parkinson’s disease – How continuous symptom and treatment response monitoring can enable better clinical decision making – Interim results from an observational study
Objective: To investigate how continuous objective information on motor symptoms and treatment response combined with subjective patient reported insights can be used to optimize Parkinson’s…REM sleep behavior disorder and Prodromal Parkinson’s Disease in patients with Essential Tremor
Objective: To assess the prevalence of REM sleep behaviour disorder (RBD) and Prodromal Parkinson's Disease (PPD) in Essential Tremor (ET) and to characterize these sub-groups…Association of Gaucher-related and Parkinson’s-private GBA1 variants with progression of PD: A longitudinal mixed model analysis.
Objective: To compare progression of motor- and non-motor symptoms in people with Parkinson’s disease (PD) with Gaucher-related gene glucocerebrosidase (GBA1) variants compared to people with…Genetic Study of polymorphism of cytokines in Parkinson’s disease.
Objective: The aim of our study was to conduct a cohort that demonstrates genetic variations in cytokines genes involved in the physiopathology, the development and…Contribution of Genetics to Onset of PD with Leg Tremor
Objective: To determine frequency and determinants of resting tremor in the leg as first motor symptom in Parkinson Disease (PD), especially as related to age…Determining and Leveraging Local Ancestry to Assess Individual-Level Risk: from the Global Parkinson’s Genetics Program
Objective: We develop a scalable pipeline leveraging existing tools to determine local ancestry for all individuals in the Global Parkinson’s Genetics Program (GP2), aiming to…Understanding diffusion in extracellular space in synucleinopathy
Objective: To understand the extracellular space (ECS) diffusion in synucleinopathy. Background: The pathogenic mechanisms underlying synucleinopathies involve the spread and propagation of α-synuclein aggregates throughout…Levels of change in interleukin-6 levels according to clinical stages of Parkinson’s disease in patients with and without Covid-19
Objective: Comparison of serum IL-6 levels in clinical stages Parkinson's disease patients with and without Сovid-19. Background: Elevated levels of the cytokine IL-6 may indicate…Age-associated Changes in Microglial Morphology and its Role in Deciphering Susceptibility to Parkinson’s Disease
Objective: To delineate the age-associated changes in microglial morphotypes in the substantia nigra pars compacta (SNpc) of C57BL/6J and CD-1 mice and alterations in response…Neuropeptide Alterations in Parkinson’s Disease: A Meta-Analysis
Objective: To analyze the levels of different neuropeptides in patients with Parkinson’s disease (PD) compared to healthy individuals. Background: Neuropeptides are bioactive molecules that play…
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