Video-guided Optimization of Stimulation Settings in Patients with Parkinson’s Disease and Deep Brain Stimulation
Objective: To investigate whether video-based evaluations of motor control and changes of predefined stimulation parameters via patient programmer can improve motor status in Parkinson’s disease…Detection of Parkinson’s Disease by Analysis of Smooth Pursuit Eye Movements and Machine Learning
Objective: The present study investigates an automatic method to parameterize smooth pursuit eye movements (SPEM) and to differentiate Parkinson's disease (PD) from controls using machine…Inflammatory changes in subjects with de novo Parkinson’s disease
Objective: To examine whether inflammation is present in subjects newly diagnosed with Parkinson’s disease (PD). Background: Evidence for the role of inflammation in PD has…Diagnostic Accuracy of Parkinson’s disease: Where Do We Stand?
Objective: To provide an up-to-date assessment of diagnostic accuracy parameters at early and late stages of the diagnosis in clinical practice and MDS Diagnostic Criteria…A Report from Japan on Initial Experiences with Adaptive Deep Brain Stimulation Therapy for Patients with Advanced Parkinson’s Disease
Objective: Here we present our initial experience with deep brain stimulation therapy (DBS) for Parkinson's disease (PD) using the closed-loop system. Background: Although DBS is…Remote identification of early, sensor-based markers of Parkinson’s Disease using participants’ smartphones: The Parkinson Progression Marker Initiative Digital sub-study
Objective: To summarize the design of the Parkinson’s Progression Markers Initiative (PPMI) Digital sub-study. The study objective is to identify the earliest signs and symptoms…Progress of the UK Cholinesterase inhibitor to prevent falls in Parkinson’s disease (CHIEF-PD) trial
Objective: This abstract provides an overview of the progress of the CHIEF-PD trial. Background: Falls are a common and debilitating consequence of Parkinson’s disease (PD).…A novel alpha-synuclein gene (SNCA) missense variant in an Austrian familiy with atypical neuropathological features
Objective: To offer clinical, genetic and neuropathological information in a novel alpha-synuclein gene (SNCA) missense variant to further our understanding of synucleinopathies. Background: Around 5–10% of…Validating a virtual Timed Up and Go (vTUG) test in Parkinson’s Disease.
Objective: To validate the vTUG as a means of remotely monitoring patient gait and balance in the home. Background: The current regulatory gold standard for…Affected tongue movements in idiopathic REM sleep behavior disorder
Objective: In Parkinson’s disease (PD), recognition of speech deviations often follows clinical diagnosis. But what if speech is a prodromal biomarker in PD? The study…
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