Effects of fine particulate matter and cigarette smoking on MPTP-induced dopaminergic neuronal cell death: Implication for Parkinson’s disease
Objective: The objective of this study was to determine the potential neurotoxicity of fine particulate matter (FPM) and the neuroprotective properties of nicotine in the pathogenesis…Homozygous PRKN exon 3 deletion in an early-onset Parkinson’s disease family from the Kadazan-Dusun ethnic group indigenous to Sabah, Malaysia
Objective: To determine the causal gene for early-onset Parkinson’s disease (PD) in a Malaysian family of Kadazan-Dusun ethnicity. Background: Among Asian populations, relatively little is…GBA variants in a multi-ethnic Parkinson’s disease (PD) cohort in Malaysia
Objective: To investigate the frequency of Glucocerebrosidase (GBA) gene variants in a multi-ethnic Parkinson’s disease (PD) cohort in Malaysia. Background: GBA variants have been associated…Providing Genetic Testing and Genetic Counseling to the Parkinson’s Disease Community: the PD GENEration Pilot Study Experience
Objective: A pilot study was conducted to assess the feasibility of offering widespread genetic testing and counseling to patients with Parkinson’s disease (PD) in the…Systematic review of cognitive subtypes derived from data driven approaches in Parkinson’s disease
Objective: To consolidate the current literature pertaining to cognitive subtypes derived using data-driven methods in Parkinson’s Disease (PD). Background: Recent application of the Mild Cognitive…Cognitive reserve in non-demented patients with Parkinson’s disease might protect against amyloid burden effect on cognition
Objective: To evaluate the effect of cognitive reserve (CR) in patients with Parkinson’s disease (PD) without dementia. Background: CR concept is a principal factor explaining…Differentiating Gait Impairments in Early Parkinson’s Disease and Early Dementia with Lewy Bodies
Objective: To characterize and differentiate gait deficits early on in individuals with DLB and PD. Background: Dementia with Lewy bodies (DLB) and Parkinson’s disease (PD)…FINANCIAL COST OF PARKINSON’S DISEASE IN BRAZIL IN THE LAST 10 YEARS
Objective: Analyzing the financial cost of Parkinson's Disease in Brazil in the last 10 years Background: The Parkinson's disease is a neurodegenerative disease that when…Inhibition of GluN2D-containing NMDA receptors alleviates the loss of dopaminergic neurons and behavioral deficits in 6-OHDA-induced model of Parkinson’s disease
Objective: The aim of this study is to explore whether the inhibition of GluN2D-containing NMDA receptors (NMDAR2D) can delay the pathological manifestations of Parkinson's disease…Opicapone in Parkinson’s Disease German Patients with Motor Fluctuations: Findings from the OPTIPARK Study
Objective: To evaluate opicapone (OPC) when used in everyday clinical practice conditions to treat Parkinson’s disease (PD) patients with motor fluctuations. Background: OPC proved to…