Postoperative change of local field potentials of subthalamic nucleus during and after period of microlesion effect of implantation of deep brain stimulation lead.
Objective: To study changes in beta oscillation before and after microlesion effect in deep brain stimulation (DBS) lead implantation. Background: Increased beta oscillation has been…Inhibition of LRRK2 kinase activity promotes glucocerebrosidase transport to the lysosomes in primary monocyte-derived macrophages from patients with GBA-associated Parkinson’s disease
Objective: The aim was to evaluate the effectiveness of leucine-rich repeat kinase 2 (LRRK2) kinase activity inhibition in restoring transport of the enzyme glucocerebrosidase (GCase),…Wavelet-based bracketing, time-frequency beta-burst detection: new insights in Parkinson’s disease
Objective: To identify bursts in wide frequency bands and show the relation between burst features and clinical scores. Background: Beta burst activity is a pathophysiological…Exploring patient-physician communication in Parkinson’s disease management: a qualitative analysis
Objective: To explore the unmet needs in patient-physician communication from different perspective.To explore the unmet needs in patient-physician communication from different perspective. Background: Patient-physician communication…Neuroprotective properties of arylpiperazine-sulphonamides in an in vitro model of Parkinson’s disease
Objective: To investigate the neuroprotective effects of novel arylpiperazine compounds as measured by viability of SH-SY5Y cells in vitro. Background: Parkinson’s disease (PD) is a…Continuous subcutaneous levodopa/carbidopa infusion with ND0612 for patients with Parkinson’s disease and motor fluctuations: Results from the Phase 3 randomized, active-controlled BouNDless study
Objective: Determine the efficacy, safety, and tolerability of ND0612 versus oral immediate-release levodopa/carbidopa (IR-LD/CD) in people with Parkinson’s disease (PwP) experiencing motor fluctuations. Background: ND0612…Safety assessment of pimavanserin in Parkinson’s disease psychosis patients: Evidence from a systematic review and meta-analysis of randomized controlled trials
Objective: This systematic review and meta-analysis aimed to assess the safety profile of pimavanserin in Parkinson’s disease psychosis (PDP) patients from the available randomized controlled…Utility of neurophysiological markers in clinical management of subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson’s disease (PD)-a case report.
Objective: Use local field potentials (LFP) to inform longitudinal clinical decision making. Background: Genetic status, clinical and stimulation parameters affect outcomes in PD STN DBS.…Does baseline expectation of benefit predict outcome in SURE-PD3, a Randomized, Double-Blind, Placebo-Controlled, Phase III trial of Inosine in Parkinson’s disease?
Objective: To evaluate the association of patient-reported baseline expectation with efficacy outcomes in a randomized placebo-controlled trial (RCT) in PD. Background: Expectation of benefit can…Analysis of levodopa use in patients with Parkinson’s Disease during pregnancy: a systematic review of the last twenty years
Objective: To evaluate the role of oral levodopa in patients with Parkinson’s disease (PD) during pregnancy, using the available literature, in order to determine the…
- « Previous Page
- 1
- …
- 243
- 244
- 245
- 246
- 247
- …
- 436
- Next Page »