Reliability of Indonesian Version Wearing Off Questionnaire
Objective: This study measure the reliability of Indonesia version wearing off (WO) questionnaire for PD patients. Background: The wearing off phenomenon is disabling complication of…First Case Series on the use of a High Frequency Vibrotactile Stimulation and Cueing Device in Panama
Objective: To assess the use of Focussed Vibrotactile Stimulation and Cueing Device (FVCD) in two patients with Parkinson's disease (PD) Background: We present two patients…Are GDNF receptors the gatekeepers of GDNF efficacy during progressive nigrostriatal neuron loss?
Objective: To determine if GDNF receptor expression levels in the striatum or substantia nigra (SN) change in relation to differences in tyrosine hydroxylase (TH) and…Genetic outcomes of South Asian Parkinsonism cohort: from a tertiary care hospital
Objective: To identify the genetic heterogeneity in 16 south Asian patient with Parkinson’s disease. Background: Parkinson’s disease(PD) is the second most progressive neurodegenerative disorder with…Clinical toolkits to improve conversations about Parkinson’s dementia
Objective: To co-produce, with people living with Parkinson’s and professionals, a pair of toolkits to improve conversations about Parkinson’s dementia in the clinic: one for…Experience of the LARGE-PD protocol in a health center in Buenos Aires, Argentina
Objective: Disseminate and inform the activity of the Latin American Research Consortium on the Genetics of Parkinson's Disease (LARGE-PD) in Argentina. Background: The LARGE-PD consortium…The epigenetic association of Parkinson’s disease risk gene- GPNMB rs199347 with drinking
Objective: This paper examines the epigenetic association of rs199347 polymorphism variants of the GPNMB with drinking and DNA methylation changes. Background: Neuroinflammatory response induced by alcohol…Does hyposmia induce apathy in early Parkinson’s disease? Lessons from structural brain connectivity
Objective: To study changes in microstructural integrity of white matter tracts associated with apathy in patients with early Parkinson’s disease (PD) and hyposmia Background: Smells…LRRK2 kinase activity regulates sphingolipid hydrolase enzymatic activities in different cell lines: induced pluripotent stem cell-derived dopaminergic neurons, primary monocyte‐derived macrophages and SH-SY5Y
Objective: To assess whether inhibition of the kinase activity of LRRK2 affects changes in enzyme activity of sphingolipid hydrolase in the culture of dopaminergic neurons…Use of concomitant medications before and after treatment with levodopa/carbidopa intestinal gel in patients with advanced Parkinson’s disease: summary of phase 3 and real-world studies
Objective: Evaluate the use of concomitant Parkinson’s disease (PD) medications before and after treatment with levodopa/carbidopa intestinal gel (LCIG) using data from phase 3 clinical…
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