Serum uric acid as a putative biomarker in Prodromal Parkinson’s disease: Longitudinal data from the PPMI study.
Objective: Our present study assessed the role of serum uric acid as a putative biomarker in a prodromal PD cohort [REM Sleep Behavior disorder (RBD)…Cognitive impairment in patients with Alzheimer’s disease and Parkinson’s disease
Objective: To compare the results of a neuropsychological study in patients with Alzheimer's disease and Parkinson's disease. Background: Recently, Parkinson's disease (PD) is increasingly considered…Low dose trihexyphenidyl use causes cognitive dysfunction in Parkinson’s disease patients.
Objective: Evaluate cognitive performance in Parkinson's disease patients receiving a low dose of trihexyphenidyl (THP). Background: Before L-Dopa's discovery, anticholinergic drugs were among the first…The application of Next Generation Sequencing in the Parkinson Disease.
Objective: This study aims to better investigating the pathogenetic of PD and improving the diagnostic approach in the molecular genetics, using the NGS. Background: Parkinson’s…The lack of association between UQCRC1 and Parkinson’s disease in a southwest Chinese population
Objective: To further investigate the association between ubiquinol-cytochrome c reductase core protein I (UQCRC1) and Parkinson’s disease (PD) among ethnic Chinese from southwest China. Background:…Gut dysbiosis in Parkinson’s disease with motor complications
Objective: We aimed to identify gut dysbiosis in Parkinson's disease patients with motor complications. Background: Recently, several evidences suggest that the gut microbiota is associated…Molecular investigation of apparently healthy heterozygous Parkin mutation carriers
Objective: To investigate whether apparently healthy individuals carrying a heterozygous pathogenic Parkin (PRKN) mutation show molecular phenotypes of mitochondrial dysfunction. Background: Homozygous or compound-heterozygous mutations…α-synuclein and deficits of membrane trafficking in Parkinson’s Disease
Objective: Aim of the study is to understand the physical and functional relationships between the PD-associated protein α-synuclein and some of the Soluble N-ethylmaleimide-sensitive-factor Attachment…Resting-state connectivity predictors for prefrontal cortex activity during walking in Parkinson’s disease.
Objective: Investigating whether resting-state brain connectivity can predict prefrontal cortex activity (PFCA) during walking for patients with Parkinson's disease (PD) and reflect the benefits of…BASELINE OLFACTION TESTING IN PARKINSON’S DISEASE PATIENTS IS CORRELATED WITH LONG-TERM DOPAMINERGIC DENERVATION IN STRIATAL SUB-REGIONS: LONGITUDINAL DATA FROM THE PPMI STUDY.
Objective: The aim of the current study was to determine whether there are longitudinal differences in dopaminergic denervation of striatal sub-regions [signal reduction in 123I-FP-CIT…
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