Pre-operative predominance of Tremor versus PIGD scores in drug OFF state predicts motor and non-motor outcomes of STN-DBS for Parkinson’s disease
Objective: To test the predictive value of predominance of tremor versus PIGD scores on the motor and non-motor outcomes of bilateral STN DBS for Parkinson’s…Integrated safety analysis of BIA-28-6156 phase 1 clinical trials (a novel allosteric activator of beta-glucocerebrosidase)
Objective: To describe the safety profile and tolerability of BIA-28-6156 observed during phase 1 clinical trials. Background: BIA-28-6156 is a novel allosteric activator of beta-glucocerebrosidase…Unveiling the Link between Stress-Related Disorders and Dysautonomic Symptoms in Parkinson’s Disease: A Cross-Sectional Study
Objective: To explore the link between post-traumatic stress disorders and dysautonomic symptoms in Parkinson's disease. Background: Parkinson's disease is a complex condition that can lead…Comparison of the MIBG uptake in the major salivary glands between progressive supranuclear palsy/corticobasal syndrome and Parkinson’s disease
Objective: To compare the MIBG uptake in the major salivary gland between progressive supranuclear palsy/corticobasal syndrome (PSP/CBS) and Parkinson’s disease (PD). Background: 123I-metaiodobenzylguanidine (MIBG) myocardial…Choroidal changes in Parkinson’s disease: A longitudinal follow up study
Objective: The objective of the study was to evaluate the longitudinal changes in the choroid layer of the eye in patients with Parkinson’s disease (PD).…Effect of the COVID-19 pandemic on gait and other motor and non-motor symptoms in people with Parkinson’s disease
Objective: To determine if the COVID-19 pandemic significantly impacted disease progression in people with Parkinson's disease (PwPD) Background: Few cross sectional and short-term longitudinal studies…A strategic training framework for building research capacity in the Global Parkinson’s Genetics Program (GP2)
Objective: To promote and facilitate learning internationally with resources and expertise to serve the training needs of the Global Parkinson’s Genetics Program (GP2;www.gp2.org) and its…Progression of striatocortical dysfunction in Parkinson’s disease: a longitudinal combined PET and fMRI study
Objective: To investigate the longitudinal progression of striatal dopaminergic dysfunction and its consequences on functional connectivity (FC) networks and clinical progression in Parkinson's disease (PD)…Explainable deep learning based detection of Parkinson’s changes in MRI brain scans
Objective: A pilot study using an AI-based framework to classify routine brain scans as Parkinson’s disease (PD) or control. Background: Prospective neuroprotective treatments for PD…Sympathetic tone abnormalities in subjects at risk for Parkinson’s Disease without evidence of nigrostriatal neurodegeneration: a multimodal biomarker study
Objective: To study autonomic dysfunction in subjects with idiopathic REM sleep behavior disorder (iRBD) and at least one pre-motor symptom of Parkinson's disease (PD). Background:…
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