Cognitive Function in Late-life and Parkinson’s Disease Neuropathology at Death
Objective: To examine the association between cognitive function in late-life and Parkinson’s disease (PD) neuropathology at death, including 1) neuron loss in the locus coeruleus…Demographic and Regional Variation in All-Cause Mortality Rates among United States Medicare Beneficiaries with Parkinson’s Disease
Objective: To determine whether all-cause mortality rates among persons with Parkinson’s disease (PD) in the United States (US) differ by sex, race/ethnicity, or geographic location.…Newly identified cases of parkinsonism and prodromal PD in a remote LRRK2 G2019S cohort
Objective: To evaluate new cases of prodromal PD and concern for parkinsonism in a cohort of LRRK2 G2019S carriers. Background: LRRK2 G2019S is a common…Bis(monoacylglycerol) phosphate levels are elevated at baseline in carriers of pathogenic variants in LRRK2 and GBA1 and do not predict progression of PD in PPMI cohorts
Objective: To assess: (a) effects of LRRK2 and GBA1 pathogenic variants on baseline urinary bis(monoacylglycerol) phosphate (BMP) levels in those with and without Parkinson’s disease…Longitudinal combined 11C UCB J and 18F FE PE2I PET imaging of presynaptic terminal loss in early Parkinson’s disease.
Objective: To longitudinally assess presynaptic terminal loss in vivo over a 2-year period in people with early Parkinson’s disease (PD). Background: Imaging tools that allow…Use of a wearable medical device for LCIG tube adjustment: a user case
Objective: To identify objectively the change in motor symptoms in a patient with Parkinson’s Disease (PD) on levodopa-carbidopa intestinal gel (LCIG) treatment with and without…Remote Assessment of Tremor using Wearable Sensors in Parkinson’s Disease Research
Objective: To describe wearable sensor-derived measures in Parkinson’s disease (PD) research. Background: Many commonly used outcome measures of PD are subjective, rater dependent, and infrequently…Is motor symptoms asymmetry a possible predictor of short-term motor outcome of bilateral STN-DBS in Parkinson’s disease?
Objective: To evaluate if the body side of motor symptoms onset may predict the short-term motor outcome of bilateral subthalamic nucleus deep brain stimulation (STN-DBS)…Synaptic Zn2+ Contribution to Parkinson’s Disease Pathophysiology: Pharmacological & Genetic Studies in Preclinical Mouse Models
Objective: The potential involvement of synaptic Zn2+ in development of Parkinson’s disease (PD) motor symptoms and dopaminergic neurodegeneration was investigated. Background: The progressive degeneration of…The relationship between cognitive function, fear of falling, and history of fall in people with Parkinson’s disease
Objective: The main aim of this study was to investigate the relationship of cognitive function with fear of falling (FOF) and falls in people with…
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