Does baseline expectation of benefit predict outcome in SURE-PD3, a Randomized, Double-Blind, Placebo-Controlled, Phase III trial of Inosine in Parkinson’s disease?
Objective: To evaluate the association of patient-reported baseline expectation with efficacy outcomes in a randomized placebo-controlled trial (RCT) in PD. Background: Expectation of benefit can…Analysis of levodopa use in patients with Parkinson’s Disease during pregnancy: a systematic review of the last twenty years
Objective: To evaluate the role of oral levodopa in patients with Parkinson’s disease (PD) during pregnancy, using the available literature, in order to determine the…Apathy, white-matter microstructure, and effort-based decision making in Parkinson’s Disease
Objective: To investigate the influence of reward and effort on behavior in PD patients with and without apathy, using a drift-diffusion model to analyze neuroimage…First case of sporadic ATP6AP2 Mutation reported in Asia in a Parkinson’s Disease patient
Objective: Genetic analysis of Parkinson's Disease (PD) with features of spasticity by Whole Exome Sequencing (WES) and use of its result for treatment modification to…Needs and priorities of people with Parkinson’s and care partners regarding neuropsychiatric symptoms
Objective: To examine the experiences of people with Parkinson’s disease (PD) and care partners (CPs) regarding cognitive, mood, behavioral, and sleep issues. Background: Neuropsychiatric symptoms…Restless legs syndrome may be associated with freezing of gait, start hesitation and falls in Parkinson’s disease
Objective: We aimed to assess the association between RLS and freezing of gait, start hesitation and falls. Background: Parkinson’s disease (PD) is a neurodegenerative disease…Modulation of pallidal activity by circadian rhythms: a new variable to be accounted for closed-loop DBS?
Objective: To analyze the influence of circadian rhythmson local field potentials (LFPs) recorded in the Globus Pallidus Internal (GPi) of patients with Parkinson’s disease (PD).…Olfactory discrimination differentiate drug-induced parkinsonism and Parkinson’s disease
Objective: In this study, we evaluated detailed differential features of olfactory function in PD and DIP. Background: DIP is common but it is challenging to…Dietary protein redistribution influences the efficacy of levodopa/carbidopa intestinal gel (LCIG) infusion
Objective: To compare levodopa/carbidopa intestinal gel (LCIG) with equally distributed dietary protein (Diet_EDP) versus restricted to twice daily (Diet_RP) and Mediterranean diet (Diet_M). Background: Levodopa…Pupil response is impaired in clinically isolated REM Sleep Behavior Disorder and Parkinsons’ Disease
Objective: Since easily accessible (bio-) markers are needed to predict progression and outcome in prodromal stages of neurodegenerative diseases this study was designed to evaluate…
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