Deep brain stimulation impacts functional brain connectivity in Parkinson’s disease.
Objective: Deep-brain stimulation (DBS) became a successful method to treat Parkinson’s disease (PD), particularly with stimulating the subthalamic nucleus (STN-DBS), although the precise mechanisms mediating…Efficacy of a four-strain probiotic on gut dysbiosis, motor and non-motor symptoms in Parkinson`s disease: a multicentre randomised controlled trial
Objective: To evaluate the effect of a four-strain probiotic (Lacticaseibacillus rhamnosus, Enterococcus faecium, Lactobacillus acidophilus, Lactiplantibacillus plantarum) on gut microbiota composition, motor and non-motor symptoms…Clinical characterization of Parkinson’s disease patients with LRRK2 mutation: Insights from a Portuguese reference center
Objective: This study aims to provide a clinical characterization of Parkinson's disease (PD) patients with LRRK2 mutations, who are being treated at a Portuguese reference…Understanding rehabilitation care utilization in Parkinson’s disease
Objective: The aim of our study was to examine experiences with rehabilitation services by people with Parkinson’s disease (PD) and their care partners (CP). Background:…Effect of multi-strain probiotics on gut microbiome and metabolites in Parkinson’s Disease
Objective: We investigated the effects of multi-strain probiotics administration on gut microbiome and metabolites, and markers of intestinal permeability and inflammation. Background: Probiotics have been…Baseline fluid biomarkers in a phase 2 clinical trial in Parkinson’s Disease
Objective: To evaluate baseline CSF and blood-based biomarkers of pathology in early-stage Parkinson’s Disease (PD) participants in the phase 2 clinical trial PASADENA. Background: Observational…PDQ-39 predicts quality of life improvement following neurostimulation for Parkinson’s disease: Prospective observational study
Objective: The primary outcome was assessing QoL of a cohort of patients with PD before and after undergoing DBS surgery, measured using PDQ-39 questionary. Secondary…Detecting clinical fluctuations in chronic biomarker recordings: experiences with chronic subthalamic peak beta band recordings in a large Parkinson’s disease patient cohort
Objective: Since the understanding of electrophysiological biomarker dynamics during every-day activities is crucial for adaptive deep brain stimulation (aDBS), this study aims to investigate characteristics…Subjective cognitive decline as predictor of objective cognitive decline in Parkinson’s patients
Objective: The present study cross-sectionally and longitudinally explores the predictive value of subjective cognitive decline (SCD) regarding objective cognitive decline in a large clinical sample…Action- and emotion-related language abilities in Slovenian-speaking individuals with Parkinson’s disease – a background normative study
Objective: To prepare action-related (AR) and emotion-related (ER) linguistic stimuli in Slovenian language to test language functions in Parkinson's disease (PD) patients. Background: PD patients…
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