- Machine Learning and Instrumented Gait Analysis to Classify Subthalamic DBS States in Parkinson’s DiseaseObjective: This study investigates whether gait features derived from an instrumented walk can predict specific treatment conditions (stimulation frequency and medication status) in a cohort…
- Longitudinal assessment of quality of life in early Parkinson’s disease: 5-year follow up studyObjective: To determine changes in HR-QoL in early PD patients during a 5-year follow up period. Background: There is limited evidence on longitudinal changes in…
- Factors that negatively impact the sexual function of women living with Parkinson’s diseaseObjective: To investigate the impact of motor and non-motor alterations and couple adjustment on sexual function in women living with PD in Brazil. Background: Among…
- LRRK2 Inhibition by BIIB122: Trial designs for two efficacy and safety studies in Parkinson’s disease patients with and without LRRK2 mutations (Lighthouse and Luma)Objective: Describe Luma and Lighthouse, two studies that investigate efficacy and safety of BIIB122, a LRRK2 inhibitor. Background: Increased LRRK2 kinase activity has been linked…
- Level of glial neurotrophic factor in the blood plasma depending on the duration of Parkinson’s diseaseObjective: To study the level of glial neurotrophic factor in the blood plasma depending on the duration of PD. Background: Study of the biochemical aspects…
- The potential impact of physical activity to increase serum a-klotho levels in people with Parkinson’s diseaseObjective: To evaluate, summarize and discuss the available literature concerning the potential effect of physical exercise on serum a-klotho levels in people with Parkinson’s disease.…
- Implementing a Neuropalliative Care Curriculum for Neurology Residents Focused on Neurodegenerative DiseasesObjective: To implement a neuropalliative care curriculum for neurology residents in order to increase comfort with palliative and hospice care topics for patients with progressive…
- Longitudinal healthcare utilization and costs in Parkinson disease : from pre-diagnosis to 9 yearsObjective: The aim of this study was to characterize attributable healthcare utilization and costs in Parkinson disease (PD) in newly diagnosed PD patients managed by…
- Outcome of Movement Disorders affected by Covid-19: case series from a single Movement Disorders UnitObjective: The aim of this study is to investigate the effects of corona virus (Covid-19) infection on patients with movement disorders. Background: Since the outbreak…
- Data Driven Paths to Advancing Precision Medicine Strategies for Parkinson’s Disease: Critical Path for Parkinson’s ConsortiumObjective: An update on the accomplishments of the Critical Path for Parkinson’s (CPP) Consortium. Background: The pharmaceutical pipeline for Parkinson’s disease (PD) is rapidly expanding. Data sharing will facilitate decision making during the development…
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