The GlyT1 inhibitor bitopertin reduces in the 6-OHDA-lesioned rat model of Parkinson’s disease
Objective: To determine the effect of glycine transporter 1 (GlyT1) inhibition with bitopertin on dyskinesia in the 6-hydroxydopamine (6-OHDA)-lesioned rat model of Parkinson’s disease (PD).…OPTIMIPARK Questionnaire:a tool to optimize treatment in Parkinson´s disease.
Objective: To validate the OPTIMIPARK questionnaire as a tool to help the clinician in the adjustment of dopaminergic treatment in Parkinson´s disease(PD). Background: At early…Opicapone in clinical practice in Parkinson’s disease patients with motor fluctuations and complications of therapy at baseline: findings from the OPTIPARK study
Objective: This post-hoc analysis evaluated the effects of opicapone (OPC) treatment in patients with Parkinson’s disease (PD) who experience motor fluctuations and complications of therapy…The responsiveness of arm swing to dopaminergic medication in Parkinson’s disease depends on task complexity
Objective: The aim of this study is to analyse the responsiveness of arm swing during walking to dopaminergic medication in patients with Parkinson’s disease. Background:…THE THERAPEUTIC EFFECT OF Bacopa monnieri (WATERHYSSOP) IN TREATING PARKINSON’S DISEASE
Objective: To determine the lethal concentration (LC50) of Bacopa monnieri aqueous extraction toward zebrafish. To analyse the behavioural study of zebrafish that has been exposed to rotenone…Serum uric acid as a putative biomarker in Prodromal Parkinson’s disease: Longitudinal data from the PPMI study.
Objective: Our present study assessed the role of serum uric acid as a putative biomarker in a prodromal PD cohort [REM Sleep Behavior disorder (RBD)…Cognitive impairment in patients with Alzheimer’s disease and Parkinson’s disease
Objective: To compare the results of a neuropsychological study in patients with Alzheimer's disease and Parkinson's disease. Background: Recently, Parkinson's disease (PD) is increasingly considered…Low dose trihexyphenidyl use causes cognitive dysfunction in Parkinson’s disease patients.
Objective: Evaluate cognitive performance in Parkinson's disease patients receiving a low dose of trihexyphenidyl (THP). Background: Before L-Dopa's discovery, anticholinergic drugs were among the first…The application of Next Generation Sequencing in the Parkinson Disease.
Objective: This study aims to better investigating the pathogenetic of PD and improving the diagnostic approach in the molecular genetics, using the NGS. Background: Parkinson’s…The lack of association between UQCRC1 and Parkinson’s disease in a southwest Chinese population
Objective: To further investigate the association between ubiquinol-cytochrome c reductase core protein I (UQCRC1) and Parkinson’s disease (PD) among ethnic Chinese from southwest China. Background:…
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