Stratified genome-wide association study revealed novel interactions for the top hit Parkinson’s disease loci.
Objective: To identify genetic modifiers and interactors that may modulate known risk variants in the SNCA, TMEM175 and MAPT loci in Parkinson’s disease (PD). Background:…Targeted plasmaproteome identifies a distinct biomarker panel in early and prodromal Parkinson’s disease
Objective: To identify protein biomarkers in plasma of patients with Parkinson’s disease (PD). Background: Inflammation plays a key role in the initiation and progression of…PD phenotype with premotor RBD is associated with a dysbiotic profile of gut microbiota.
Objective: The aim of the study was to compare the fecal microbial composition of a group of PD patients with and without premotor RBD. Background:…Cerebral white matter atrophy may be associated with the performance of activities of daily livings in patients with Parkinson’s disease
Objective: To assess whether global or regional brain structural abnormalities are associated performance of activities of daily livings (ADL) in patients with Parkinson's disease (PD).…Patterns of Cortical Thinning in Patients with Parkinson’s Disease
Objective: To investigate patterns of cortical thickness that are associated with disease severity and response to levodopa. Background: Cortex affection is a neuropathological correlate of…Relationship of subcortical iron deposition and mitochondrial dysfunction in patients with idiopathic Parkinson’s disease
Objective: To investigate subcortical brain iron deposition as a potential predictor of the bioenergetic status in patients with idiopathic Parkinson's disease. Background: The underlying pathophysiology…Analysis of brain structural connectivity networks and white matter integrity in patients with early Parkinson’s disease: a longitudinal study
Objective: The objective of this study was to analyze the differences in structural connectivity and white matter (WM) microstructural integrity in people with early-PD over…Impact of the postural function сhanges on quality of life and daily activity in patients with Parkinson’s disease during DBS
Objective: Quality of life (QOL) and activity of daily living (ADL) in PD patients depends on the severity of motor disorders, including changes of postural…PARKINSON’S DISEASE AND COVID-19 PANDEMIC: MODIFICATIONS IN MOTOR AND NON-MOTOR SYMPTOMS AND IN THE ACCESS TO MEDICAL AND NON-MEDICAL CONSULTATIONS AND TREATMENTS
Objective: The objective was to determine in a group of PD patients their perception of how isolation measures during the pandemic affected their motor and…Olfactory dysfunction in incidental Lewy body disease and Parkinson’s disease: An update
Objective: Using a larger sample size compared to our previous study, we evaluated the relationship between olfactory dysfunction based on the University of Pennsylvania Smell…
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