Parkinson’s Disease Duration at Total Knee Arthroplasty and 5-Year Vascular and Periprosthetic Outcomes: A Nationwide Matched Cohort Study
Objective: The objective of the study was to evaluate whether Parkinson's disease (PD) is associated with long-term risks of vascular events (cardiovascular and cerebrovascular) and…Considering Oral Health to Optimise the Potential for Current and Future Treatments in Parkinson’s Disease
Objective: To determine if the Oral Health Assessment Questionnaire (OHAQ) devised by 2 Parkinson’s Disease Nurse Advanced Practitioners (PDNAP) could facilitate a healthier mouth to…DTI-ALPS index and its association with dopamine loss, brain metabolism, and motor and cognitive manifestations in Parkinson’s disease
Objective: This study aimed to investigate the clinical relevance of glymphatic dysfunction in Parkinson's disease (PD) by integrating the diffusion tensor imaging (DTI) analysis along…Neuroinflammation and neurodegeneration biomarkers in Parkinson’s disease: integration of neuroimaging and fluid markers
Objective: To investigate the association between serum and cerebrospinal fluid (CSF) levels of NfL and GFAP and dopaminergic degeneration measured by 123I-ioflupane SPECT (DaTSCAN) in…Clinical and Genetic Profile of the ACTIVATE Population: A Phase 2 Trial of BIA 28-6156 in GBA-PD
Objective: To characterize the patient population enrolled in the ACTIVATE study, a Phase 2 multicenter, randomized, double-blind, placebo-controlled trial assessing the efficacy, safety, tolerability, pharmacodynamics,…External Validation of a Machine Learning Classifier for Motor Progression in Parkinson’s Disease
Objective: To externally validate a previously published machine learning (ML) classifier for predicting motor symptom progression in Parkinson’s disease (PD) using an independent clinical dataset.…5-year Longitudinal Changes in Non-motor Symptoms and Their Association With Motor Progression in Parkinson’s Disease
Objective: To examine longitudinal relationships between non-motor symptoms (NMS) and motor progression in Parkinson’s disease (PD), and to determine whether baseline NMS predict motor decline…Clinical feasibility of a semi-automated Olfactometry System in α-Synucleinopathies
Objective: To evaluate the feasibility, performance, and diagnostic accuracy of a semi-automated olfactometry system (NOS-DX1000) for standardized assessment of olfactory dysfunction in α-synucleinopathies. Background: Olfactory…Temporally Patterned Deep Brain Stimulation Improves Gait Metrics and Freezing of Gait in Parkinson’s Disease
Objective: To investigate the clinical impact of temporally patterned deep brain stimulation (DBS) on gait and Freezing of Gait (FoG) in Parkinson’s disease (PD). Background:…Parkinson’s Disease and Parkinsonism Family Center Psychoeducational Program for Patients and Caregivers
Objective: To provide structured psychoeducational and informational support, including disease education, coping and self-management strategies, and guidance on healthcare and social services for Parkinson’s disease…
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