Theta-Burst Subthalamic Nucleus Deep Brain Stimulation Enhances Segregation of Cognitive Networks in Parkinson’s Disease
Objective: This study investigates the effects of a novel TBS paradigm on large-scale brain network connectivity in PD patients. Background: Parkinson’s disease (PD) is a…The differential transcriptomic signatures of substantia nigra in Parkinson disease and Multiple system atrophy
Objective: To investigate transcriptomic signatures of Parkinson's disease (PD) and the Parkinsonian subtype of Multiple System Atrophy (MSA-P) in the substantia nigra pars compacta (SNpc).…Bayesian Re-Analysis of Phase I and II Subthalamic Nucleus Perfusion Changes Following Mesenchymal Stem Cell Infusion in Parkinson’s Disease
Objective: To compare subthalamic nucleus (STN) perfusion changes following mesenchymal stem cell (MSC) infusion in Parkinson’s disease (PD) using Bayesian methods in both Phase I…Impact of Patient-Specific Structural Connectivity of STN-DBS on Balance and Mobility – Pilot study
Objective: To evaluate the impact of patient-specific structural connectivity between VTA in STN targeting and SMA/preSMA on functional mobility improvements in PD patients undergoing DBS.…The Genetic Landscape of Parkinson’s Disease in African and Admixed Populations: Discovering Population-Specific Risk and Unveiling Etiological Insights
Objective: To perform the largest PD risk genome-wide association study (GWAS) in the African and African admixed populations. Background: Investigating the genetic foundation of Parkinson’s…First Insights into Genetic Findings from the Mexican Parkinson’s Research Network (MEX-PD): The Case of MTHFR
Objective: To present the first genetic findings of the MEX-PD cohort, with a specific focus on analyzing the role of MTHFR variants Background: Despite significant…A unique genetic duality: GAK and SCN4A Mutations in Myasthenic Syndrome and Early-Onset Parkinsonism in a Peruvian woman: A Case Report
Objective: To present the first genetically characterized non-linear summative damage characterized case resulting in early-onset parkinsonism associated with congenital myasthenia Background: The GAK (Cyclin G…Gene-Caffeine Interaction in Parkinson’s Disease: A Case-Control Study of Alpha-synuclein SNPs
Objective: Investigating the interaction between genetic susceptibility and caffeine intake in modulating Parkinson’s disease (PD) risk. Background: PD arises from a complex interplay of genetic…Oculomotor Differences in PARK2 PD: a Study of Structured and Unstructured Eye Movements in an Irish Genetic Cohort
Objective: To identify and measure how eye movements differ between biallelic PARK2 carriers, carriers of a single PARK2 variant and non-carriers using structured and unstructured…Correlation between the microlesional effect of subthalamic deep brain stimulation and postoperative imaging in Parkinson’s disease
Objective: To characterize the clinical improvement associated with MLE and its temporal progression. In addition, to analyze postoperative images and investigate whether there is a…
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