Autonomic Coupling Patterns Differ by REM Sleep Behavior Disorder Status in De Novo Parkinson’s Disease
Objective: To investigate the relationships between autonomic dysfunction, clinical severity, and striatal dopaminergic deficits in de novo Parkinson’s disease (PD), and to determine whether these…Probiotic Y7 Intervention Is Associated with Improved Motor, Gut-Related, and L-DOPA-Related Outcomes in a Rat Model of Parkinson’s Disease
Objective: To evaluate whether probiotic Y7 intervention improves disease-related outcomes and influences L-DOPA-related responses in a 6-hydroxydopamine (6-OHDA) rat model of Parkinson’s disease (PD). Background:…Peripheral Inflammatory Biomarkers as Predictive Indicator for Parkinson’s Disease: a Systematic Review and Meta-Analysis
Objective: To evaluate the association between peripheral inflammatory biomarkers and the incidence of Parkinson’s disease. Background: Parkinson’s disease is a progressive neurodegenerative disorder in which…Prevalence and Clinical Determinants of Cognitive Impairment in a Diverse Parkinson’s Disease Cohort
Objective: To estimate the prevalence of cognitive impairment in a diverse Parkinson’s disease (PD) cohort and explore its associations with vascular, motor, and non-motor determinants.…Immunological characteristics of Parkinson’s disease by clinical form and stage
Objective: To analysed of IL-10 concentrations in serum of patients with PD. Background: IL-10 is a key pro-inflammatory cytokine involved in the regulation of microglia…Network determinants of stimulation-induced speech impairment after subthalamic DBS in Parkinson’s disease
Objective: To delineate hemisphere-specific, local, and network-level mechanisms underlying stimulation-induced speech impairment after subthalamic deep brain stimulation (STN-DBS). Background: STN-DBS can improve but also worsen…MDSGene literature update on autosomal recessive Parkinson’s Disease
Objective: To comprehensively characterize demographic, genetic, and phenotypic features in individuals with autosomal recessive Parkinson’s disease (PD), leveraging individual-level data from published literature. Background: In…Health-Related Quality of Life in patients with Parkinson’s disease based on the ICF model
Objective: to identify the leading domains of functioning in patients with Parkinson's disease (PD) based on the International Classification of Functioning, Disability and Health (ICF).…Subthalamic low-frequency activity reflects engagement during live sports viewing
Objective: To investigate subthalamic nucleus (STN) low-frequency dynamics during emotional engagement while watching live sports in patients with Parkinson's disease treated with adaptive deep brain…Metabolomic profile as a biomarker of non-motor symptoms severity in patients with Parkinson’s disease
Objective: To investigate possible associations between serum metabolomic profiles and non-motor symptoms (NMS) frequency and intensity in PD patients Background: Metabolomic studies are providing growing…
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