Peripheral neuropathy (NP) in advanced Parkinson’s disease (PD) patients treated with continuous subcutaneous foslevodopa/foscarbidopa (fLD/fCD)
Objective: To assess peripheral NP occurrence and clinico-electrophysiological features in patients with advanced PD patients treated with continuous subcutaneous fLD/fCD. Background: Continuous subcutaneous fLD/fCD is effective…Impact of TRPV4 Deletion on Nociception in an Experimental Model of Parkinson’s Disease Non-Motor Symptoms
Objective: This study investigated the role of the TRPV4 receptor in nociceptive regulation using an experimental model of Parkinson’s disease (PD) focused on non-motor manifestations.…Point-of-Care Neuromuscular Ultrasound With Fractal Biomarkers for Stratification of Neuropathic and Myogenic Drivers of Motor Decline
Objective: We investigated whether a structured ultrasound protocol integrating fascicular morphometry, fractal image analysis, and AI-assisted classification can stratify neuropathic versus myogenic contributors to motor…Natural History of Sialidosis Type I: A Prospective Longitudinal Follow-Up Study of Clinical and Electrophysiological Markers
Objective: We performed a prospective analysis to determine the natural history as well as changes of electrophysiological markers in a cohort of Sialidosis type I.…Identification of Cerebrotendinous Xanthomatosis in Patients with Neurodegenerative Disorders from the Cincinnati Cohort Biomarker Program
Objective: To develop an algorithm for identifying patients with cerebrotendinous xanthomatosis (CTX) in a cohort of individuals with neurodegenerative disorders. Background: CTX is a rare…Schindler Disease (a Rare Autosomal Recessive Lysosomal Storage Disorder)
Objective: This case report discusses the diagnostic difficulties and treatment strategies for Schindler disease type III and provides insightful information on its clinical manifestations Background:…A Case of CANVAS Misdiagnosed as Subacute Labyrinthitis and Meniere’s Disease
Objective: To report a case of CANVAS initially misdiagnosed as subacute labyrinthitis and Meniere’s disease, highlighting the diagnostic challenges and the importance of recognizing this…Painful Legs Moving Toes Syndrome in Rural Western India: Etiological Spectrum and Outcomes in 24 Cases
Objective: To characterize clinical profiles, etiological patterns, and therapeutic outcomes of Painful Legs Moving Toes syndrome [PLMTS] patients in a rural Indian neurology practice. Background:…Relationship Between Motor Subtypes and Central and Peripheral Neurodegeneration in Early Parkinson’s Disease: A Study Using DAT SPECT and SUDOSCAN
Objective: To investigate the relationship between Parkinson’s disease (PD) motor subtypes and neurodegeneration in both the central and peripheral nervous systems using dopamine transporter single-photon emission…Evaluation of Nociception in a Model of Parkinson’s Disease for the Study of Non-Motor Symptoms in Trpv4-/- Animals
Objective: This study aimed to investigate the role of the TRPV4 receptor in regulating the nociception in a PD model experimental for the study of…
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