MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Pharmacotherapy"

  • 2019 International Congress

    Subacute Encephalopathy with Pimavanserin Treatment in Parkinson Disease

    J. King, G. Volkell, J. Wyant, E. Molho (Albany, NY, USA)

    Objective: To report 3 cases of drug-induced encephalopathy in patients treated with pimavanserin (PVN) for Parkinson disease (PD) related psychosis (PDP). Background: Quetiapine and clozapine,…
  • 2019 International Congress

    Influence of disease duration in the efficacy response of Parkinson’s disease patients with motor fluctuations: post-hoc analysis from combined BIPARK-I and II

    H. Gama, J. Ferreira, A. Lees, A. Antonini, O. Rascol, A. Santos, D. Magalhães, J. Rocha, P. Soares-da-Silva (Coronado, Portugal)

    Objective: To evaluate the impact of disease duration on the efficacy of opicapone (OPC) in levodopa-treated Parkinson’s Disease (PD) patients with motor fluctuations. Background: OPC,…
  • 2019 International Congress

    Efficacy of opicapone in Parkinson’s disease patients according to baseline rasagiline use: a post-hoc analysis from combined BIPARK-I and II

    A. Lees, J. Ferreira, O. Rascol, W. Poewe, E. Tolosa, H. Gama, D. Magalhães, J. Rocha, P. Soares-da-Silva (London, United Kingdom)

    Objective: To evaluate opicapone’s (OPC) efficacy in levodopa-treated Parkinson’s Disease (PD) patients with or without concurrent rasagiline use (CRU). Background: OPC, a once-daily COMT inhibitor,…
  • 2019 International Congress

    Association of genetic polymophisms with pharmacokinetics of levodopa in South indian PD patients

    R. Borgohain, T. Sd, T. Syed, V. Kutala, R. Kandadai, S. Meka, S. Tandra (Hyderabad, India)

    Objective: To evaluate the role of COMT gene variations on the pharmacokinetics (PK) of L-dopa in PD patients. Background: Genetic variations in enzymes (MAO-B, COMT),…
  • 2018 International Congress

    7 years later, are the Tomlinson’s levodopa dose equivalencies proposed consensual?

    E. Dellapina, F. Ory-Magne, A. Sommet, V. Rousseau, D. Devos, S. Thobois, L. Defebvre, C. Brefel-Courbon, JC. Corvol, O. Rascol, F. NS-PARK/FCRIN Network (Toulouse, France)

    Objective: (i) To collect all the levodopa equivalent doses (LED) formulae and references used in clinical trials in Parkinson’s disease (PD) since the publication of…
  • 2018 International Congress

    Personal KinetiGraph™ Movement Recording System: An Assessment of Utility in a Movement Disorder Clinic

    F. Nahab, H. Abuhussain, L. Moreno (La Jolla, CA, USA)

    Objective: The objective of this open-label study was to evaluate the clinical utility of the Personal KinetiGraph™ (PKG) Movement Recording System in the care of…
  • 2018 International Congress

    Weight variation in Parkinson’s disease patients treated with levodopa-carbidopa intestinal gel infusion

    B. Fernández-Rodríguez, J. Dupouy, E. Harroch, MH. Fabre-Delcros, C. Barthélémy, P. Loubière, K. Barange, C. Brefel-Courbon, O. Rascol, F. Ory-Magne (Toulouse, France)

    Objective: To compare weight variations between three cohorts of patients with advanced Parkinson’s disease (PD): patients during their first year of treatment either with levodopa-carbidopa…
  • 2018 International Congress

    Therapeutic Drug Monitoring and Pharmacogenetic Tests as Tools in Pharmacovigilance of Anti Parkinson’s Therapy

    N. Verma (Baddi, India)

    Objective: Parkinson's disease (PD) is the second most prevalent neurodegenerative disease worldwide, affecting more than 7 million people worldwide. However, treatment outcome in many patients…
  • 2018 International Congress

    Ondansetron, a highly-selective 5-HT3 receptor antagonist, alleviates L-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson’s disease

    C. Kwan, I. Frouni, D. Bédard, A. Hamadjida, P. Huot (Montreal, QC, Canada)

    Objective: To determine the effectiveness of selective serotonin 3 (5-HT3) receptor blockade at reducing the severity of established, and preventing the development of, dyskinesia. Background:…
  • 2018 International Congress

    Association between serum Vitamin D levels and Parkinson’s disease: A systematic review and meta-analysis

    XY. Luo, R. Ou, HF. Shang (Chengdu, China)

    Objective: The aim of this systematic review and meta-analysis was to evaluate the association between serum vitamin D levels and the risk and severity of…
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