Comparisons of cerebral glucose metabolism and striatal DAT binding in PD patients with and without RBD
Objective: This study aims to identify the differences of functional neuroimaging phenotype between Parkinson’s disease (PD) patients with REM sleep behavior disorder (RBD) (PD+RBD+) and…In vivo staging of pathology in REM sleep behaviour disorder
Objective: To study the level of dysfunction in the peripheral and central nervous system in idiopathic REM sleep behaviour disorder (iRBD) patients. Background: α-synuclein (α-syn)…Automated Differential Diagnosis of Parkinsonian Syndromes Using FDG-PET Metabolic Brain Network Analysis
Objective: To discriminate among parkinsonian patients using an automated network analysis of FDG-PET brain images. Background: Clinical differentiating among parkinsonian syndromes: Parkinson’s disease (PD), multiple…A Florbetapir [F18] amyloid PET Imaging study in Parkinson’s disease Dementia (PDD): The influence of amyloid deposition on cognitive status and course of disease progression
Objective: To determine whether amyloid deposition, as assessed by PET imaging with the [18F]-Florbetapir, is related in patients with Parkinson Disease and Dementia (PDD) to…α4β2-nicotinic receptor availability in Parkinson’s disease MCI and healthy controls: A pilot imaging study using [18F]-XTRA PET
Objective: We aimed to show that a radiotracer with high affinity to cortical and hippocampal α4β2-nicotinic cholinergic receptors (1) would be reduced in regions associated…Dopaminergic dysfunction and abnormal metabolic network activity in REM sleep behavior disorder
Objective: This study is to investigate the correlations between the abnormalities in the distribution of striatal dopamine transporter (DAT) and the expression of Parkinson's disease…Imaging of phosphodiesterase 10 A (PDE10A) enzyme levels in the living human brain of Huntington’s disease gene expansion carriers and healthy controls with positron emission tomography.
Objective: The objective of this study was to examine the loss of Phosphodiesterase 10A enzyme (PDE10A) across a broad spectrum of Huntington’s disease (HD) stages.…F-18-DOPA-PET predicts impulsive behavior under dopaminergic therapy in Parkinson patients
Objective: The aim of this study is to investigate the influence of the intensity of dopaminergic projections to the ventral striatum (VS) measured with F-18-DOPA-PET…Clinical characteristics of cognitive impairment in patients with Parkinson’s disease and its related pattern in 18F-FDG PET imaging
Objective: To characterize the clinical features and the neuroanatomical bases of cognitive impairment in Parkinson’s disease (PD) with respect to attention, executive function, memory, language,…Phosphodiesterases and striatal pathways in Parkinson’s disease
Objective: To use phosphodiesterase (PDE)10A ([11C]IMA107) and PDE4 ([11C]Rolipram) positron emission tomography (PET) molecular imaging combined with diffusion tensor imaging (DTI) based probabilistic tractography to explore the expression…
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