DBS of the STN in 44 patients with Parkinson’s disease – Radiological and clinical outcome
Objective: Precision in implantation of deep brain stimulation (DBS) electrodes relies on systematic interdisciplinary planning and intra-operative testing and needs to be discussed along with…Safety of deep brain stimulation for movement disorders: A single-centre long-term standardized recording and analysis
Objective: To analyze the long-term safety of Deep Brain Stimulation (DBS) procedures for patients with movement disorders. Background: DBS is currently indicated to treat several…Modulation of microglia function in the prion-like spreading of α-synuclein in the murine brain
Objective: We aimed to analyze the influence of two microglia-related pathways on the accumulation of α-synuclein aggregates and neurodegeneration after intracerebral injection of sonicated murine…Piperine potentiates neuroprotective effect of curcumin in MPTP model of Parkinson’s disease in rats: Impact on neurochemical modulation
Objective: (1) Curcumin is well tolerated phenolic compound used for CNS disorder but problem is its low oral bioavailability and (2) Piperine is combined to…Finding an optimal lead trajectory for a better stimulated volume in movement disorder therapy
Objective: Defining the best lead trajectory (Arc; Ring) with a computational 3D stereotactic model of the Globus Pallidus internus (GPi) and investigating the influence of…Reflex saccades changes can estimate long-term symptom progression in DBS STN and MED Parkinson’s disease patients (PD)
Objective: The aim of this study was to evaluate the impact of STN DBS on RS parameters in PD. We have compared disease progression in…The impact of STN DBS on kinetic tremor in Parkinson’s disease patients
Objective: The aim of the study is to evaluate the impact of STN DBS on kinetic tremor in PD patients in comparison to pharmacologically treated…
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