Synchronization Study of Regional Local Field Potential in Rat with Dopamine Receptor Stimulation
Objective: The aim of this study attempts to explore the non-linear interaction with cross-frequency coupling in rats during the stimulation of dopamine receptors. Background: Investigating…Change of extracellular glutamate and GABA level in striatum during deep brain stimulation of the entopeduncular nucleus in rats
Objective: Globus pallidus interna (GPi) is recognized as an effective treatment for advanced Parkinson’s disease. However, the neurochemical basis of its effects remains unknown. The…Phosphodiesterase 10A and cognition in Parkinson’s disease
Objective: We aimed to assess the associations between Phosphodiesterase 10A (PDE10A) expression in the executive striatum and cognitive performance in vivo, using [11C]IMA107 PET and…Imaging biomarker for progression of motor symptoms in advanced Parkinson’s disease
Objective: The aim of the present study is to clarify correlation between motor deficits and dopaminergic neuronal loss in advanced Parkinson’s disease (PD). Background: Series…The Use of Diffusion Weighted Imaging to Detect Structural Biomarkers in Recently-Diagnosed Parkinson’s Disease Patients
Objective: To quantify biomarkers for recently-diagnosed PD patients in the midbrain and their dopaminergic connections to the striatum. Background: The development of improved PD treatments…Closed loop spinal cord stimulation restores locomotion and desynchronizes corticostriatal beta oscillations
Objective: To test if closed loop Spinal Cord Stimulation (SCS) could be used to restore locomotion in a 6-hydroxydopamine (6-OHDA ) rodent model of Parkinson's…Longitudinal decline in white matter integrity in Parkinson’s disease: An analysis of Parkinson Progression Markers Initiative diffusion tensor imaging data
Objective: To determine the relative changes in white matter integrity as measured by diffusion tensor imaging (DTI) magnetic resonance imaging (MRI) in PD patients relative…Contribution of individual motor signs to striatal dopamine deficiency in parkinsonism
Objective: The primary aim of the study was to investigate if any individual motor sign could be used clinically to predict striatal dopamine deficiency. Secondary…A longitudinal PET study to assess progression of laterality in Parkinson’s disease
Objective: This study aims to identify in Parkinson’s disease (PD) whether striatal dopamine transporter (DAT) losses occur at a similar rate in both sides of…Alteration to Basal Ganglia Morphology in Freezing of Gait in Parkinson’s Disease
Objective: To characterize the subcortical grey matter adaptations related to Freezing of Gait in Parkinson’s Disease (PD). Background: Owing to its connections with motor, cognitive…
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