Safety and Efficacy of unilaterally Focused Ultrasound Subthalamotomy in Early Parkinson´s Disease: The EARLY FOCUS I Study
Objective: To assess the safety and efficacy of unilateral FUS subthalamotomy in early PD patients. Background: FUS subthalamotomy is feasible and therapeutically effective in Parkinson´s…Expectations of DBS: the patient’s perspective
Objective: To examine the evolution and change of the treatment-related expectations of patients with advanced Parkinson’s Disease (PD) before and during treatment with bilateral deep…Relations between subthalamic alpha oscillations and motor control impairment in Parkinson’s Disease patients
Objective: Our goal was to investigate subthalamic movement-related oscillatory dynamics in PD patients with different symptom severity. Background: Stable oscillations at frequencies 8-30 Hz in…Long-term efficacy of unilateral high-intensity focused ultrasound subthalamotomy for Parkinson’s Disease
Objective: To explore the long-term safety and efficacy of focused ultrasound subthalamotomy (FUS-STN). Background: Unilateral MRI-guided high-intensity FUS-STN improves motor signs of Parkinson’s disease (PD) [1]…Spectral somatotopy of the human subthalamic nucleus in Parkinson’s disease
Objective: This study aims to systematically investigate the spatial segregation of a wide range of spectral features of local field potentials (LFPs) within the STN…Real-World Outcomes Using a Novel Directional Lead from a Multicenter DBS Registry for Parkinson’s Disease
Objective: In this report, real-world outcomes using Directional Deep Brain Stimulation (DBS) Systems with multiple independent current source control (MICC) for use in managing symptoms…Sweetspot analysis of Deep Brain Stimulation in Parkinson´s disease: Beyond the subthalamic nucleus?
Objective: To study the relationships between clinical response and leads location -in a cohort of Parkinson’s disease (PD) patients and deep brain stimulation of subthalamic…Apathy and Volume of Tissue Activated (VTA) following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Cohort
Objective: To determine frequency and/or predictors of improvement or worsening of apathy, we evaluated this behavior among those who received bilateral subthalamic deep brain stimulation…Phase-amplitude coupling between beta power and high frequency oscillations as a sensitive marker of parkinsonian state.
Objective: The aim of this work was to study the potential clinical usefulness of the phase-amplitude coupling (PAC) between beta power and high frequency oscillations (HFO´s).…Markers of Parkinson-related impulsive-compulsive behaviors in the activity of single units in the subthalamic nucleus
Objective: To characterize the features of the activity of single neurons of the subthalamic nucleus associated to impulsive-compulsive behaviors (ICBs) in Parkinson’s Disease (PD). Background:…
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