Evaluation of apathy before and after subthalamic nucleus deep brain stimulation therapy in advanced Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) has been approved to relieve the motor symptoms of Parkinson's disease (PD) patients when the optimal pharmachologic treatment is unsatisfactory.…Levodopa and subthalamic stimulation do not have the same effect on subjective cost for distal and axial efforts in Parkinson’s disease
Objective: To compare the effects of levodopa and subthalamic nucleus stimulation (STN-DBS) on decision-making tasks for distal (hand) and axial (speech) efforts in Parkinson’s disease…An Objective Tool to Guide Target Selection for DBS in PD (GPi vs STN)
Objective: To create a simple tool to aid in selection of the proper target for Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD). Background: Two…Firing rate and proportion of subthalamic oscillatory neurons increase associated with more advanced Parkinson’s Disease
Objective: To explore whether neuronal firing rate and proportion of oscillatory neuronal activity in the subthalamic nucleus (STN) is associated with severity in patients with…Comparison of neuropathology in Parkinson’s disease subjects with and without deep brain stimulation
Objective: The aim of this postmortem study was to compare, in Parkinson's disease subjects with and without bilateral subthalamic nucleus deep brain stimulation (STN-DBS), the…Evaluation of spike sorting algorithms applied to artificial spikes and to spikes recorded from the Subthalamic Nucleus of PD patients
Objective: To evaluate the variability in spike sorting results using different clustering algorithms Background: Extracellular currents recorded from the Subthalamic Nucleus (STN) of PD patients,…Comparison of pallidal and subthalamic deep brain stimulation in Parkinson’s disease: therapeutic and adverse effects
Objective: To compare the therapeutic and adverse effects of the globus pallidus interna (GPi) and subthalamic nucleus (STN) deep brain stimulation (DBS) for the treatment…Effectiveness of lead position with MER to determine STNs: A study of MER with DBS for quantifying the effects of DBS in Parkinson`s disease
Objective: To quantify the effectiveness of MER with DBS, characterize Parkinson`s disease symptoms/extract MER signal features of STN Background: Parkinson`s disease targeting CNS, causing group of neurons…Effect of deep brain stimulation of the subthalamic nucleus on cranial tremor in Parkinson’s disease
Objective: To analyze the effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) on cranial tremor in Parkinson’s disease (PD). Background: STN DBS…Feasibility of utilizing the NIH Toolbox in Parkinson’s disease subjects with deep brain stimulation
Objective: To determine the feasibility of utilizing the NIH Toolbox in moderate to advanced disease Parkinson’s disease (PD) subjects with bilateral subthalamic nucleus deep brain…
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