Ecologically Valid, Ambient, Longitudinal, and Unbiased Assessment of Treatment Efficacy in Parkinson’s Disease (EVALUATE-PD)
Objective: To determine the feasibility of using in-home digital biomarkers (DBs) and activity monitoring for clinical trials and studies of early Parkinson’s Disease (PD) and…Smartphone-based digital assessments in the LUMA trial of BIIB122 for early-stage Parkinson’s disease
Objective: To evaluate the sensitivity of routine smartphone-based performance assessments in the free-living environment as part of a randomized clinical trial in Parkinson’s disease (PD).…Ultrasound of Spinal Fluid Dynamics in Headache and Vertigo Patients with Central Sensitization: Novel Biomarker
Objective: This study aimed to investigate the neurophysiological responses and potential mechanisms underlying the therapeutic effects of ultrasound (US)-guided dry needling in patients presenting with…Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease
Objective: To investigate the longitudinal relationship between changes in dopamine transporter single-photon emission computed tomography (DaT SPECT) and changes in motor symptom severity in Parkinson’s…Developing Composite Digital Measures for Tracking Parkinson’s Disease (PD) Progression using a Comprehensive Machine Learning-based Framework
Objective: To develop composite digital measures that could be used to track disease progression in early PD patients, and to determine whether they can outperform…Reliability of Digital Measures in Parkinson’s Disease and Their Implications for Sample Size Calculations
Objective: Assess the reliability and measurement error of measures derived from digital health technologies (DHTs) in Parkinson’s Disease (PD) patients and estimate sample size for…Signs of Respiratory Dysfunction across Parkinson’s Disease Spectrum
Objective: The aim of the study is to investigate signs of respiratory dysfunction across the Parkinson’s disease spectrum. Background: Respiratory dysfunction in Parkinson’s disease (PD)…Actigraphy wear compliance across CNS disorders
Objective: Examine actigraphy wear compliance in 5 neurological-disorders clinical trials using an ActiGraph GT9X Link with additional compliance features Background: Wrist worn biometric devices are…Natural history and disease progression biomarkers of multiple system atrophy: the ASPIRE-MSA study
Objective: To evaluate multiple system atrophy (MSA) disease progression on a panel of candidate MSA biomarkers pre-selected for their putative involvement in the pathophysiology of…Multimodal Conversational AI for Remote Patient Monitoring and Analysis of Parkinson’s Disease
Objective: To present, analyze and evaluate a cloud-based audio-visual dialog agent and its associated automated speech, face and movement analytics for remote patient monitoring in…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.