MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Surrogate endpoints"

  • 2024 International Congress

    Ultrasound of Spinal Fluid Dynamics in Headache and Vertigo Patients with Central Sensitization: Novel Biomarker

    R. Bubnov (Kyiv, Ukraine)

    Objective: This study aimed to investigate the neurophysiological responses and potential mechanisms underlying the therapeutic effects of ultrasound (US)-guided dry needling in patients presenting with…
  • 2024 International Congress

    Dopamine Transporter Imaging as Monitoring Biomarker in Parkinson’s Disease

    V. Dzialas, G. Bischof, K. Möllenhoff, A. Drzezga, T. van Eimeren (Cologne, Germany)

    Objective: To investigate the longitudinal relationship between changes in dopamine transporter single-photon emission computed tomography (DaT SPECT) and changes in motor symptom severity in Parkinson’s…
  • 2024 International Congress

    Developing Composite Digital Measures for Tracking Parkinson’s Disease (PD) Progression using a Comprehensive Machine Learning-based Framework

    S. Zhai, J. Ren, J. Shen, S. Chatterjee, Y. Xu, A. Liaw, V. Svetnik, O. Patil, ER. Dorsey, J. Adams, M. Dockendorf, R. Baumgartner (Rahway, USA)

    Objective: To develop composite digital measures that could be used to track disease progression in early PD patients, and to determine whether they can outperform…
  • 2024 International Congress

    Reliability of Digital Measures in Parkinson’s Disease and Their Implications for Sample Size Calculations

    J. Lavine, A. Scotina, S. Haney, E. Izmailova, L. Omberg (New York, USA)

    Objective: Assess the reliability and measurement error of measures derived from digital health technologies (DHTs) in Parkinson’s Disease (PD) patients and estimate sample size for…
  • 2023 International Congress

    Signs of Respiratory Dysfunction across Parkinson’s Disease Spectrum

    J. Janssen Daalen, P. Ainslie, H. van Hees, M. Meinders, D. Thijsse, B. Bloem (Nijmegen, Netherlands)

    Objective: The aim of the study is to investigate signs of respiratory dysfunction across the Parkinson’s disease spectrum. Background: Respiratory dysfunction in Parkinson’s disease (PD)…
  • 2023 International Congress

    Actigraphy wear compliance across CNS disorders

    J. Lavine, A. Pearlmutter, K. Momeni, R. Ellis (New York, USA)

    Objective: Examine actigraphy wear compliance in 5 neurological-disorders clinical trials using an ActiGraph GT9X Link with additional compliance features Background: Wrist worn biometric devices are…
  • 2023 International Congress

    Natural history and disease progression biomarkers of multiple system atrophy: the ASPIRE-MSA study

    N. Del Campo, P. Péran, P. Payoux, V. Rousseau, A. Drif, H. Catalá, C. Thalamas, C. Tranchant, F. Duriff, A. Marques, JP. Azulay, C. Moreau, JC. Corvol, S. Thobois, AG. Corbille, S. Frismand, B. Patterson, A. Foubert-Samier, A. Pavy-Letraon, M. Fabbri, W. Meissner, O. Rascol (Toulouse, France)

    Objective: To evaluate multiple system atrophy (MSA) disease progression on a panel of candidate MSA biomarkers pre-selected for their putative involvement in the pathophysiology of…
  • MDS Virtual Congress 2021

    Multimodal Conversational AI for Remote Patient Monitoring and Analysis of Parkinson’s Disease

    V. Ramanarayanan, A. Exner, D. Pautler, S. Snyder, H. Kothare, J. Liscombe, D. Suendermann-Oeft, A. Lambert, R. Kohlmeier, J. Huber (San Francisco, USA)

    Objective: To present, analyze and evaluate a cloud-based audio-visual dialog agent and its associated automated speech, face and movement analytics for remote patient monitoring in…
  • MDS Virtual Congress 2020

    Alpha-synuclein and Amyloid beta peptide 1-42 in Parkinson’s disease and parkinsonian plus syndrome cohorts

    G. Babu, M. Gupta, V. Paliwal (Lucknow, India)

    Objective: To evaluate the serum levels of α-synuclein (α-syn) and Amyloid β 1-42 (Aβ1-42) in the patients of Parkinson’s disease (PD), progressive supranuclear palsy (PSP)…
  • 2019 International Congress

    Stability and reliability of objective measures of speech in Parkinson’s Disease over 12 months

    M. Magee, J. Tamplin, C. Marigliani, F. Baker, M. Morris, A. Vogel (Melbourne, Australia)

    Objective: To describe the stability and reliability of acoustic measures of speech in Parkinson’s Disease (PD) at 3 and 12 months. Background: Speech biomarkers hold…
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