MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Tauopathies"

  • 2023 International Congress

    CSF tau reflects long-term outcome of patients with idiopathic normal pressure hydrocephalus: a longitudinal retrospective study.

    J. Bissacco, C. Simonetta, D. Mascioli, N. Mercuri, T. Schirinzi (Roma, Italy)

    Objective: To predict long-term clinical outcome of iNPH patients through a panel of neurodegeneration-related CSF biomarkers. Background: Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative…
  • 2023 International Congress

    Tau PET imaging in a patient with progressive supranuclear palsy-parkinsonism-a case report

    S. Su, Y. Weng, K. Lin, I. Hsiao, K. Huang, C. Lu (Taoyuan City, Taiwan)

    Objective: Early detection of the brain tau deposition in patients with progressive supranuclear palsy-parkinsonism (PSP-P) by 18F-PMPBB3 positron emission tomography (PET) imaging. Background: PSP is…
  • 2023 International Congress

    Creation of a biobank of patients with Progressive Supranuclear Palsy and Corticobasal Syndrome in Argentina

    B. Couto, G. Mizraji, M. Maza, S. Sargiotto, F. Greloni, I. Paez Paz, E. Avale, T. Falzone (Buenos Aires, Argentina)

    Objective: To generate a longitudinal cohort study and a research-ready biobank of Argentinian patients with corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP). Background: Corticobasal…
  • 2023 International Congress

    Amyloid status differentiates synaptic loss and atrophy in Corticobasal Syndrome.

    N. Holland, G. Savulich, P. Jones, D. Whiteside, D. Street, M. Naessens, M. Malpetti, Y. Hong, T. Fryer, T. Rittman, E. Mulroy, F. Aigbirhio, K. Bhatia, J. O'Brien, J. Rowe (Cambridge, United Kingdom)

    Objective: In this observational/cross-sectional study, we tested whether the degree and extent of in vivo synaptic loss differed in patients with corticobasal syndrome according to…
  • 2023 International Congress

    CBS presenting rapidly progressive anterior operculum syndrome with suggested background pathology of 4-repeat tauopathy by tau PET: A case report

    K. Nakamura, Y. Kuroha, M. Hatakeyama, A. Kimura, Y. Nakamura, Y. Murakami, M. Watanabe, H. Igarashi, T. Takahashi, H. Shimada (Niigata city, Japan)

    Objective: Report of a case with suspected TDP-43 proteinopathy as the pathological background in the early stage of the disease, and a final diagnosis of…
  • 2023 International Congress

    Introducing the molecular subtyping of Progressive Supranuclear Palsy: a proof of concept

    I. Martinez-Valbuena, S. Lee, E. Santamaria, J. Fernandez-Irigoyen, B. Couto, N. Reyes, H. Tanaka, S. Forrest, A. Kim, H. Qamar, J. Li, A. Karakani, K. Senkevich, E. Rogaeva, N. Visanji, A. Lang, G. Kovacs (Toronto, Canada)

    Objective: To enhance understanding of the molecular mechanisms underlying disease heterogeneity in Progressive supranuclear palsy (PSP) Background: PSP is a 4R-tauopathy characterised by subcortical pathology…
  • 2023 International Congress

    Transferrin as a possible CSF biomarker in neurodegenerative proteinopathies

    K. Mensikova, P. Kanovsky, K. Klicova, D. Konickova, S. Kurcova, M. Nevrly, P. Otruba, Z. Grambalova, M. Kaiserova, J. Zapletalova (Olomouc, Czech Republic)

    Objective: The aim of this study was to determine whether cerebrospinal fluid (CSF) levels of transferrin differ between patients with Parkinson´s disease (PD), multiple system…
  • 2023 International Congress

    Phenotypic characterization of 104 patients with Progressive Supranuclear Palsy: A Tertiary care experience from South India

    R. Yadav, S. Dey, N. Kamble, V. Holla, R. Mahale, M. Debnath, P. Pal (Bangalore, India)

    Objective: To prospectively evaluate and subtype the patients of Progressive supranuclear palsy being referred to a tertiary care movement disorders facility in South India. Background:…
  • 2023 International Congress

    Early-onset cortico-basal degeneration (CBD) due to a c.2092G>A MAPT mutation

    M. Mata Alvarez-Santullano, L. Lopez-Manzanares, J. Lopez-Lozano, N. Villares, C. Magdaleno, C. Dela Torre (Madrid, Spain)

    Objective: To describe a patient with early-onset atypical parkinsonism that evolved to a classic CBD without dementia, associated to a c.2092G>A MAPT mutation Background: Although…
  • 2023 International Congress

    Cell-specific MAPT gene expression is preserved in tau cytopathologies in Progressive Supranuclear Palsy

    S. Forrest, S. Lee, N. Nassir, V. Sackmann, I. Martinez-Valbuena1, J. Li, A. Ahmed, L. Ittner, A. Lang, M. Uddin, G. Kovacs (Toronto, Canada)

    Objective: To systematically map and quantify MAPT expression in neurons, astrocytes and oligodendroglia across different brain regions to determine whether cell type and/or regional differences…
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