MAPT mutation frontotemporal dementia with parkinsonism: when previous results can skew the diagnosis
Objective: Case report presentation. Background: In frontotemporal dementia with parkinsonism (FTDP), several mutations in MAPT gene have been identified, and numerous family cases were reported,…Lateralized Tau Pathology in a Case of Lewy Body Dementia with Corticobasal Syndrome
Objective: To measure bilateral in vivo and postmortem tau pathology in a well-characterized patient presenting with corticobasal syndrome (CBS) due to underlying neocortical stage Lewy…Plasma microRNA expression profiling in patients with progressive supranuclear palsy. A five-microRNA panel in plasma was identified as a potential biomarker for progressive supranuclear palsy
Objective: Our objective was to identify differentially expressed, circulating miRNAs in PSP which could serve as diagnostic biomarker for this disease. Background: Progressive supranuclear palsy…An evaluation of the application of clinical research criteria for corticobasal degeneration in a large clinico-pathological series
Objective: To evaluate diagnostic criteria for corticobasal degeneration (CBD) in relation to pathology and disease course. Background: The overlapping features of CBD and related conditions…Benign Progressive Supranuclear Palsy: mild pathology associated with parkinsonism
Objective: Objective: To describe the clinical presentation and neuropathology of cases where the degree of tau pathology is mild, and the neuronal loss is anatomically…Novel Cognitive Markers for Early Diagnosis and Monitoring of Progressive Supranuclear Palsy
Objective: The aim of this study was to evaluate whether a novel computerised test could offer an inexpensive and reliable tool that can aid diagnosis…Visualising tau in patients with progressive supranuclear palsy using PI2620-PET
Objective: This study investigates the use of a new tau-specific PET radiotracer, [18F]-PI-2620, as a tool for visualising tau in the living brain. Background: The…In vivo relationship between synaptic density and functional connectivity in progressive supranuclear palsy: a multimodal [11C]UCB-J PET and resting state fMRI study.
Objective: To assess the relationship between synaptic density and functional connectivity in the primary tauopathy of Progressive Supranuclear Palsy (PSP). Background: PSP is a debilitating…Long and short survival in Parkinson syndrome: pathology and genetics are key prognostic factors
Objective: To study the clinical, pathological and genetic profile of Parkinson syndrome (PS) cases that have > 20 years survival (long survival, or LS) compared…No frank biochemical evidence of proteinopathy in the cerebellar cortex of patients with essential tremor
Objective: This study was designed to determine the presence of common types of proteinopathies in the cerebellar cortex of patients who died with essential tremor…
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