Tourette – Like Phenotypes Following Combined Striatal Interneuron Loss.
Objective: To determine whether the ablation of Nkx2.1 derived striatal interneurons (SI) in mice produces Tourette-like phenotypes including abnormal movements and perseverative behaviors. Background: Tourette…Dual Target Bi Pallidal Deep Brain Stimulation in Tourette Syndrome Deciphering Neurophysiology with Chronic Local Field Potential Recordings
Objective: To investigate the neurophysiological activity of dual-target bi-pallidal DBS in Tourette Syndrome (TS) patients using chronic local field potential (LFP) recordings in an outpatient…MDS Task Force on Tic Disorders: Development of a New Classification Scheme for Tic Disorders
Objective: To establish a clear definition and axis classification scheme for tics that serves to separate phenomenology from etiology. Background: Gilles de la Tourette documented…Tourettism occurring during gender transition with testosterone therapy
Objective: Past decades have seen an increase in gender dysphoria subjects seeking hormonal treatment1,2. We report motor and vocal tics following testosterone therapy introduction for…Brain-behavior quantification and synchronization to drive closed-loop deep brain stimulation
Objective: Closed-loop DBS systems require a neural biomarker to responsively turn on stimulation, which in turn requires neurophysiological quantification synchronized to behavior or symptoms. Our…Role of the cerebellocortical pathway in the pathophysiology of adult with Tourette’s syndrome
Objective: To assess state-dependent cerebellar-cortical connectivity, through transcranial magnetic stimulation (TMS), in adult patients with Tourette Syndrome (TS) during a voluntary tic inhibition task. A…Beliefs about Tourette Syndrome in Adolescent Patients with Tics
Objective: To explore information resources and individual perceptions of causes and modifiers of Tourette Syndrome (TS) and tic disorders. Background: The development of tics is…Social media consumption in adolescents with tics
Objective: To explore the impact of social media behaviors in adolescents with tic disorders. Background: Social media has an increasing role in disseminating information and…Metagenomic exploration of the gut microbiome in a sibling-controlled pilot study of children with Tourette Syndrome
Objective: To detect gut microbial signatures of Tourette syndrome (TS) in the first sibling-controlled investigation of this condition. Background: The contribution of gut microbiome, and…The Association Between Tic Disorders and Atopy
Objective: To determine whether pediatric patients with tic disorders have an altered risk of atopy when compared with controls, whether this difference in risk is…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.