MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • MDS Virtual Congress 2021

    CVT-301 (levodopa inhalation powder) improves Patient Global Impression of Change (PGIC) over 1 year in patients with Parkinson’s disease (PD): a meta-analysis

    M. Saint-Hilaire, A. Corbin, P. Zhao, D. Kegler-Ebo (Boston, USA)

    Objective: A meta-analysis of PGIC results was performed using combined data from 3 different studies of CVT-301 in patients with PD over a total of…
  • MDS Virtual Congress 2021

    Amantadine DR/ER Efficacy as Early Add-On for Motor Complications in Parkinson’s Disease

    C. Tanner, J. Lytle, A. Formella (San Francisco, USA)

    Objective: Utilize clinical trial data to analyze amantadine delayed release/extended release (AMT DR/ER) capsules as an early add-on for OFF and dyskinesia in people with…
  • MDS Virtual Congress 2021

    Assessment of Fluctuating Parkinson’s Disease with Sensor-Based Home Monitoring-Feasibility Results

    T. Fay-Karmon, N. Galor, B. Heimler, R. Bartsch, A. Zilka, V. Livneh, M. Plotnik, S. Hassin-Baer (Ramat Gan, Israel)

    Objective: To implement home-based monitoring (HBM) using wearable devices, a smartphone dedicated app and patient reported outcomes in order to provide a more comprehensive picture…
  • MDS Virtual Congress 2021

    Registry Analysis (In Progress) to Evaluate Clinical Outcomes and Disease Burden of Advanced PD in Patients With Motor Fluctuations and Dyskinesia Managed With Oral Dopaminergic Therapies Versus Device-Aided Therapies

    W. Hu, O. Ladhani, P. Kukreja, A. Ramirez-Zamora (Gainesville, USA)

    Objective: To compare clinical outcomes of patients with Parkinson's disease (PD) with moderate and severe motor fluctuations or dyskinesia managed with oral dopaminergic medications vs…
  • MDS Virtual Congress 2021

    Indirect Treatment Comparison of Adjunctive Treatments for Patients with Parkinson’s Disease Experiencing Motor Complications

    D. Kremens, W. Oertel, R. Pahwa, R. Hauser, C. Lecureuil, R. Johnson, G. Went (Philadelphia, USA)

    Objective: Evaluate the comparative efficacy of treatment options for Parkinson's disease (PD) motor complications using indirect treatment comparison. Background: Amantadine delayed release/extended release (DR/ER) capsules…
  • MDS Virtual Congress 2021

    Influence of Dopamine Transporter Gene Polymorphism on Wearing Off

    CE. Mantese, V. Altmann, A. Schumacher-Schuh, M. Hutz, CRM. Rieder (Porto Alegre, Brazil)

    Objective: To study the influence of Dopamine transporter gene polymorphism on Wearing off (WO) through 19 items wearing off questionnaire (WOQ-19) Background: The dopamine transporter…
  • MDS Virtual Congress 2021

    Analysis of Amantadine formulations for OFF and Dyskinesia in Parkinson Disease

    W. Oertel, R. Pahwa, R. Hauser, M. Sale, G. Went (Marburg, Germany)

    Objective: Evaluate the effects of amantadine formulations on the treatment of OFF and dyskinesia in Parkinson’s patients. Background: There are currently three formulations of amantadine…
  • MDS Virtual Congress 2021

    Levodopa/carbidopa intestinal gel (LCIG) reduces fluctuations and shortens time to on without troublesome dyskinesia in advanced Parkinson’s Disease: Post-hoc analyses of 54-week LCIG-monotherapy trial

    R. Pahwa, J. Aldred, A. Merola, N. Gupta, E. Terasawa, V. Garcia-Horton, P. Kandukuri, Y. Jalundhwala, Y. Bao, O. Ladhani, S. Isaacson (Kansas City, USA)

    Objective: To assess the long-term effectiveness of LCIG monotherapy on reducing daily health-state fluctuations and time to on without troublesome dyskinesia (ONwoTD) after waking Background:…
  • MDS Virtual Congress 2021

    Safinamide Improves Pain in Parkinson´s Disease. Results from the SAFINONMOTOR Study.

    R. Yáñez, C. Labandeira, M. Cimas Hernando, I. Cabo, J. Paz González, M. Alonso Losada, M. González Palmás, C. Martínez, D. Santos García (Ourense, Spain)

    Objective: Our aim was to analyze the effectiveness of safinamide on pain in Parkinson´s disease (PD) patients from the SAFINONMOTOR (an open-label study of the…
  • MDS Virtual Congress 2020

    Prevalence, impact, and factors associated with excessive buccal saliva in the COPARK database

    S. Perez-Lloret, L. Negre-Pages, P. Damier, A. Delval, P. Derkinderen, A. Destée, M. Fabbri, W. Meissner, A. Rachdi, F. Tison, O. Rascol (Buenos Aires, Argentina)

    Objective: To describe the prevalence of sialorrhea and drooling in Parkinson’s Disease (PD) patients of the COPARK study, to find factors associated to these conditions,…
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