Metabolic connectivity assessed by dynamic FDG-fPET acquisition in Parkinson’s disease: a multimodal fPET and fMRI study
Objective: To examine the spatial convergence of hemodynamic and metabolic network characteristics based on dynamic [18F]FDG-fPET acquisition Background: While fMRI reveals within-subject hemodynamics, [18F]FDG-PET traditionally…Patterns of Parkinson disease mitochondrial brain function indexed by 31P magnetic resonance spectroscopy
Objective: To examine whether individuals with PD show greater temporal than frontal high energy phosphate metabolism (31P MRS ATP) that is similar or different from…Functional network correlates of APOE ε4 allele in Parkinson’s disease
Objective: To investigate the influence of APOE ε4 allele on metabolic network activity and functional connectivity in patients with Parkinson's disease (PD). Background: Disease progression…Network analysis of brain perfusion in [11C]UCB-J PET: Parkinson’s related motor pattern (PDRP)
Objective: The aim was to investigate the use of R1 (relative delivery parameter) as a surrogate of blood perfusion to identify brain networks specific to…The hypometabolism in anterior cingulate gyrus and thalamus: potential biomarkers of disease progression in progressive supranuclear palsy
Objective: This study aimed to identify differences in FDG uptake and metabolic covariant network (independent component analysis) in progressive supranuclear palsy (PSP) in comparison with…Machine learning diagnosis of parkinsonian syndromes: network approach with two different sites
Objective: To test an automated differential diagnostic algorithm for parkinsonian syndromes based on machine learning and FDG-PET scans using subject scores for sets of validated…Whole-brain metabolic pattern analysis of faciobrachial dystonic seizures (FBDS)
Objective: Whole-brain metabolic network analysis was performed to 1) identify the symptomatic network of faciobrachial dystonic seizures (FBDS); 2) to explore independent neuroimaging predictors; and…Analyzing the metabolic function of DJ-1 in the pathogenesis of Parkinson`s disease (PD) and Glioblastoma multiforme (GBM)
Objective: In this project, we are comprehensively studying the function of DJ-1 in PD and GBM to better understand its observed role in both, neurodegeneration…BRAIN REGIONAL HYPOMETABOLISM PROGRESSION IN iRBD: THE COGNITIVE ROLE OF OCCIPITAL HYPOMETABOLISM
Objective: To understand functional brain changes over time in isolated REM sleep behaviour disorder (iRBD), we investigated the progression of regional hypometabolism in iRBD patients…Reconfiguration of Functional Motor Connectome after MRgFUS Vim Thalamotomy in Essential Tremors
Objective: Our primary endpoint was to verify whether rs-FC between tremor-related areas was effectively modulated by MRgFUS at 1 and 3 months post-operatively. Alongside, we…