Objective: to determine the etiology of basal ganglionic disorders in a sample of Egyptian children

Background: In childhood, the metabolic activity of the basal ganglia is greater and they are particularly prone to injury. The lesions may be unilateral: in Rassmussen encephalitis, diabetes with hemichorea/hemiballism and infarction or – more frequently – bilateral in many pathologic conditions like Carbon monoxide poisoning, hypoglycemia, and Wilson disease. Damage to the basal ganglia cells may cause problems controlling speech, movement, consciousness, muscle tone and cognition.

Method: This study was conducted on 23 patients attended the Pediatric Neurology of Al-Azhar University Hospitals during a period of one year from the beginning of November 2014 to the end of November 2015. A specialized pediatric neurological sheet, Cognitive assessment in children using Stanford-Binet Intelligence Scale and Laboratory investigations were performed.

Results: acute ischemic stroke was the most frequent cause, which was found in 8 (34.8%) cases, followed by 7 (30.4%) had metabolic causes, 6 (26.1%) had infectious causes, and lastly 2 (8.7%) had toxic causes.

Conclusion: acute ischemic stroke was the most frequent cause of basal ganglionic lesion in a sample of Egyptian children.

References: – Bekiesinska-Figatowska M, Mierzewska H, Jurkiewicz E. 2013. Basal ganglia lesions in children and adults. Eur J Radiol. 82(5):837-49. – Zuccoli G, Yannes M, Nardone R, Bailey A, Goldstein A. 2015. Bilateral symmetrical basal ganglia and thalamic lesions in children: an update (2015). Neuroradiol. 57(10):973-8

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MDS Abstracts - https://www.mdsabstracts.org/abstract/etiology-and-clinical-study-of-basal-ganglionic-lesions-in-a-sample-of-egyptian-children/