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The role of dementia in Parkinson’s disease

A. Aralbayeva, A. Kondybaeva, S. Kamenova, K. Kuzhibaeva (Almaty, Kazakhstan)

Meeting: MDS Virtual Congress 2020

Abstract Number: 381

Keywords: Dementia, Parkinsonism

Category: Parkinson's Disease: Cognitive functions

Objective: To identify cognitive and visual-spatial disorders in patients with Parkinson’s disease.

Background: In the clinical picture of Parkinson’s disease, non-motor symptoms acquire great importance, which lead to disability and a decrease in the quality of life of patients. As the therapy for motor disorders improves, it is the cognitive impairment and other mental disorders that are associated with them that often come to the fore, making it most difficult to care for patients. Moreover, the presence of dementia limits the possibilities of therapy of motor disorders, as it predisposes to the occurrence of mental side effects of drugs. In addition to complaints with cognitive dysfunction, there often appear visual-spatial disorders, which are one of the manifestations of the disease unfavorable for a patient’s life, have not been studied sufficiently to date.

Method: We examined 18 women and 14 men with cognitive disorders in Parkinson’s disease. The age of patients varies from 60 to 75 years. The comparison group was comparable in age and sex, without CNS diseases.
All patients underwent clinico-neuropsychological, ophthalmological and, neuroimaging studies.

Results: In 65.6% of patients, dementia of mild severity was detected, in 28.1% of moderate severity and in 6.25% of patients with severe degree. Recognition and copying of drawings, violation of spatial orientation, psychotic symptoms affecting visual and spatial perception were worse in the PD group than in the comparison group. Visual-spatial disturbances are most pronounced in patients with Parkinson’s disease with a severe degree of dementia.
We have also developed a useful model for testing patients with Parkinson’s disease, having visual and spatial and cognitive deficits, significantly improving the quality of the examination, which is also a rehabilitation simulator with similar disorders.

Conclusion: The visual-spatial deficit is most pronounced in patients with Parkinson’s disease with severe dementia.

To cite this abstract in AMA style:

A. Aralbayeva, A. Kondybaeva, S. Kamenova, K. Kuzhibaeva. The role of dementia in Parkinson’s disease [abstract]. Mov Disord. 2020; 35 (suppl 1). https://www.mdsabstracts.org/abstract/the-role-of-dementia-in-parkinsons-disease/. Accessed June 15, 2025.
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