Session Information
Date: Monday, June 20, 2016
Session Title: Epidemiology
Session Time: 12:30pm-2:00pm
Location: Exhibit Hall located in Hall B, Level 2
Objective: There appears to be no research that has focused on the relationship between body composition phenotype and postural instability in IPD. The aim of this study was to evaluate the degree of postural instability and explore its relationship with body composition in Parkinson’s disease.
Background: Postural instability, a cardinal sign of idiopathic Parkinson’s disease (IPD) may be associated with body composition in older adults at risk of falling, but few data exist on this topic.
Methods: Cross-sectional study design (n=47 IPD and 58 sex-matched controls). Postural stability tests included: Sensory Organisation Test, Motor Control Test, Timed Up and Go with and without a cognitive dual task, and the Step Test. A DXA scanner measured body composition; Movement Disorders Society-Unified Parkinson’s disease Rating Scale assessed the degree of IPD severity; and Student t-test and stepwise regression analysis were used to investigate the relationship between body composition and postural stability.
Results: Mean group differences between IPD and controls for the equilibrium composite score, the two types of Timed Up and Go, and the Step Test were significant (p<0.05); strategy and latency composite scores and body composition variables were not. Three participants were sarcopenic; 32% of IPD participants and 41% controls were obese. In IPD, total body lean mass and age predicted latency composite scores (p<.001), and explained 11.3% and 10.8% of the variance. Disease, age, and leg fat mass predicted both types of Timed Up and Go (p<0.05), contributing 39% and 16%, respectively to variance. Sex and disease predicted the equilibrium composite score (10.5%, p< .01).
Conclusions: Participants with IPD had reduced postural stability compared to controls. Obesity was high and sarcopenia low, in the IPD group. Disease status, age and sex were influential factors in the weak relationships found between postural stability and body composition.
Recently accepted in the J of Aging Research & Clinical Practice.
To cite this abstract in AMA style:
K.S. Diab, L.A. Hale, D.L. Waters, M.A. Skinner, G. Hammond-Took. The relationship between body composition and postural instability in idiopathic Parkinson’s disease [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/the-relationship-between-body-composition-and-postural-instability-in-idiopathic-parkinsons-disease/. Accessed June 14, 2025.« Back to 2016 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/the-relationship-between-body-composition-and-postural-instability-in-idiopathic-parkinsons-disease/