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A comparison study of health-related quality of life between female and male patients with Parkinson’s disease

B. Donmez Colakoglu, T. Kahraman, E. Goz, F. Soke, A. Genc, P. Keskinoglu (Izmir, Turkey)

Meeting: 2016 International Congress

Abstract Number: 524

Keywords: Parkinsonism

Session Information

Date: Monday, June 20, 2016

Session Title: Quality of life/caregiver burden in movement disorders

Session Time: 12:30pm-2:00pm

Location: Exhibit Hall located in Hall B, Level 2

Objective: To investigate the effect of gender difference on health-related quality of life in patients with Parkinson’s disease (PD).

Background: PD has a negative impact on health-related quality of life in its sufferers. Previous studies have thoroughly investigated the clinical determinants of health-related quality of life, such as age, disease severity, motor and non-motor symptoms, in patients with PD. These studies have indicated that health-related quality of life is most affected by depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopaminergic drugs. Other factors such as gender can also affect health-related quality of life in PD.

Methods: Seventy-seven consecutive patients with PD (48% female) were included in this cross-sectional study. Health-related quality of life was evaluated with the 8-Item Parkinson’s disease Questionnaire (PDQ-8) (as a disease-specific measure of health-related quality of life) and 36-Item Short Form Health Survey (SF-36) (as a generic measure). Demographic and clinical characteristics, such as age, body mass index, disease duration and stage, determined with Hoehn &Yahr scale, were also investigated.

Results: Age, body mass index, disease duration, and Hoehn &Yahr stage were similar in female and male patients (p>0.05). This indicates that the groups were similar in terms of demographic and clinical characteristics. There was no significant difference in PDQ-8 and mental component score of SF-36 (p>0.05). On the other hand, physical component score of SF-36 was significantly lower in female patients (p<0.05).

Conclusions: This study indicates that physical health-related quality of life was more affected in female patients with PD than males. Therefore, strategies to improve and/or maintain physical functioning should be much more focused on female patients in the management of PD.

To cite this abstract in AMA style:

B. Donmez Colakoglu, T. Kahraman, E. Goz, F. Soke, A. Genc, P. Keskinoglu. A comparison study of health-related quality of life between female and male patients with Parkinson’s disease [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/a-comparison-study-of-health-related-quality-of-life-between-female-and-male-patients-with-parkinsons-disease/. Accessed June 14, 2025.
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