Category: Parkinsonism, Others
Objective: In order to alert clinicians to the possibility of the coexistence of the two diseases and optimize the management of both conditions.
Background: Parkinson’s disease (PD) and myasthenia gravis (MG) are neurological diseases with different pathophysiologies, and their coexistence is rare. Some symptoms can appear in both PD and MG, making the diagnosis of coexistence difficult.
Method: We report on a patient with PD and MG, and searched PubMed and Embase for all patients diagnosed with PD and MG, and then grouped and compared them according to different preexisting diseases.
Results: There were a total of 47 cases of concomitant PD and MG. The proportion of cases with first-onset PD followed by MG was higher than that of first-onset MG followed by PD. The proportion of female, ocular symptoms was higher, and any PD symptom and dropped head was lower in first-onset MG patients.
Conclusion: Clinicians should take a careful and thorough evaluation to give a combined diagnosis with PD and MG. More research is needed to help understand the pathogenesis of coexistence of two diseases, and to provide more therapeutic options.
To cite this abstract in AMA style:
Z. Mao, Q. Nie, Z. Li, Z. Xue. Coexistence of Parkinson’s Disease and Myasthenia Gravis: Disease Characteristics and Confusion [abstract]. Mov Disord. 2022; 37 (suppl 2). https://www.mdsabstracts.org/abstract/coexistence-of-parkinsons-disease-and-myasthenia-gravis-disease-characteristics-and-confusion/. Accessed June 15, 2025.« Back to 2022 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/coexistence-of-parkinsons-disease-and-myasthenia-gravis-disease-characteristics-and-confusion/