Session Information
Date: Wednesday, June 7, 2017
Session Title: Parkinson's Disease: Cognition
Session Time: 1:15pm-2:45pm
Location: Exhibit Hall C
Objective: In this study, we aimed to clarify the relationship between PD severity and cognitive function, depression and quality of life.
Background: We are continuing to examine the cognitive function and mental symptoms of patients with Parkinson’s disease.
Methods: For 107 PD outpatients, we evaluate MMSE and FAB for cognitive function, SDS for depression, PDQ-39 for QOL.
The subjects were divided into two groups the mild group（Ⅱ or less） and the moderate or severe group（Ⅲ or more）according to Hoehn & Yahr severity classification, and we statistically examined the test results of each group.
Results: There were 50 patients in the mild group.( mean age was 66.7 ± 8.0 years, gender was 20 males, 30 females, and the mean of disease duration was 6.6 ± 6. 9 years.) There were 57 patients in the moderate or severe group.( mean age was 70.8±8.0 years, gender was 27 males, 30 females, and the mean of disease duration was 5.3±4.6 years.)
Each test mean point and standard deviation of the mild group and the moderate or severe group were written as follows. MMSE: 26.8±2.9，26.2±3.2， FAB: 14.0±2.9，13.6±2.8， SDS: 44.8±7.8，42.0±9.5， PDQ-39: 33.3±28.7，32.8±27.2
As a result of statistically examining the difference in score between the 2 groups, no significant difference was found in any of them (p = .082～.471).
Based on the mean score of each test, in each group, the cognitive function was kept above the cut – off point and the depressed mood was kept within the normal range in many patients.
Conclusions: Regarding cognitive function, depression, quality of life, there was no difference in severity of Parkinson’s disease. Even if the motor function was impaired by the progression of Parkinson’s disease, it was shown that cognitive function and psychiatric symptoms worsened and QOL did not decrease.
To cite this abstract in AMA style:
M. Saruwatari, M. Sagawa, A. Kumon, K. Hasegawa. Consideration of the relationship between severity of Parkinson’s disease and cognitive function, depression, quality of life [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/consideration-of-the-relationship-between-severity-of-parkinsons-disease-and-cognitive-function-depression-quality-of-life/. Accessed June 15, 2025.« Back to 2017 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/consideration-of-the-relationship-between-severity-of-parkinsons-disease-and-cognitive-function-depression-quality-of-life/