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Deep Brain Stimulation in Parkinson’s Disease: Experience of the Neurology Department of Marrakesh

Z. Chourafa, M. Chraa, N. Louhab, N. Kissani (Marrakesh, Morocco)

Meeting: 2019 International Congress

Abstract Number: 2016

Keywords: Deep brain stimulation (DBS)

Session Information

Date: Wednesday, September 25, 2019

Session Title: Surgical Therapy

Session Time: 1:15pm-2:45pm

Location: Les Muses Terrace, Level 3

Objective: The authors report the experience of the Marrakesh University Hospital in Idiopathique Parkinson’s surgery.

Background: The treatment ofidiopathicParkinson’s disease (IPD) remains symptomatic and relies mainly on the use of dopaminergic drugs. Deep brain stimulation (DBS) has significantly improved the quality and life expectancy of patients but it is reserved for patients meeting well-defined selection criteria. Only 5 to 10% of Parkinson’s patients would be candidates for DBS.

Method: We conducted a retrospective study spread over an 18-month period from May 2017 to December 2018, it interested a series of 10 patients treated for IPD with DBS indicated and performed at Mohammed VI University Hospital in Marrakech. Patients with severe depression, dementia, poor general condition, and poor dopaminergic response were excluded from this study.

Results: Of the 10 operated patients, four patients were male and six female gender, sex ratio is 0.6, the age of our patients is between 51 and 68 years.The selection of patients fulfilling the BBC for IPD, the surgical technique consisted in implanting the electrode in the sub-thalamic nuclei with intraoperative electro-physiological monitoring. This therapy allowed the improvement of all tremor predominant IPD, reduction in dyskinesia in all cases, and decrease the fluctuation in time to 1h30 on averagefor all patients,80% of patients had a reduction of dopa therapy in the operating position at 50% with good improvement clinical.Reporting the following complications: two of our patients developed a hematoma and another developed a severe depression but reversible. One patient did not report improvement and chose to remain under Ldopa alone.

Conclusion: Deep brain stimulation is an effective therapy for the symptomatic treatment of Parkinson’s disease, this technique does not treat the disease or stop its natural evolution, it is reserved for patients meeting well-defined selection criteria.

To cite this abstract in AMA style:

Z. Chourafa, M. Chraa, N. Louhab, N. Kissani. Deep Brain Stimulation in Parkinson’s Disease: Experience of the Neurology Department of Marrakesh [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/deep-brain-stimulation-in-parkinsons-disease-experience-of-the-neurology-department-of-marrakesh/. Accessed June 15, 2025.
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