Session Information
Date: Wednesday, June 7, 2017
Session Title: Parkinson's Disease: Cognition
Session Time: 1:15pm-2:45pm
Location: Exhibit Hall C
Objective: The aim of this study was to assess the relationship between depression on cognitive performance in Parkinson’s disease patients.
Background: There are very few studies in India to understand cognitive functions in Parkinson’s disease(PD). This study gives an insight into the effect of Parkinson’s disease on cognitive functions.
Methods: Twenty four Parkinson’s patients were included in the study, and the subjects were set up by a median split of the scores obtained on the Centre for Epidemiological Studies – Depression Scale (CES-D).For high depression number of patients was 12 and for low depression it was 12. The PD subjects’ age range was from 45 years to 82 years. Majority of the PD subjects were right handed. The subjects’ education ranged from 4rd grade to Masters degree. Twelve subjects had high depression with a mean age of 66.17 years; 12 had low depression with a mean age of 64.23 years. The NIMHANS Neuropsychological Battery was employed. Scores were compared with age, education and gender specific norms, where scores falling below the 15th percentile of the normative data were treated as deficits. Mean, SD and t-test were used to analyse the data.
Results: The study inferred that patients on the whole did not show significant difference except for Finger Tapping Test. Individual analysis shows that cognitive impairment amongst the PD subjects is highest in Auditory Verbal Learning & Memory, the total of which is 79%, Finger tapping – Right Hand score is 75%, Left Hand score is 75%, AVLT Immediate Recall score is 67%, AVLT – DR score is 58%, ROCFT Copy score is 54%, Logical Memory IR score is 37% and ROCFT DR score is 37%. Overall, 67% of PD subjects had depressive symptoms.
Conclusions: Parkinson’s Disease subjects’ cognitive impairments are observed more in motor speed, verbal & visual memory and visuo-constructive ability
To cite this abstract in AMA style:
A.J. Jacob, S. OJ, S. K, G. Kumarpillai. Depression and Cognitive Performance in Patients with Parkinson’s Disease [abstract]. Mov Disord. 2017; 32 (suppl 2). https://www.mdsabstracts.org/abstract/depression-and-cognitive-performance-in-patients-with-parkinsons-disease/. Accessed June 14, 2025.« Back to 2017 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/depression-and-cognitive-performance-in-patients-with-parkinsons-disease/