Category: Parkinson's Disease: Non-Motor Symptoms
Objective: To analyze the risk of dysphagia, respiratory muscle strength (RMS) and maximal phonation time (MPT) in elderly with Parkinson’s disease (PD) in the initial stages Hoen & Yahr modified 0-3.
Background: It has already been demonstrated Dysphagia and vocal disorders in PD. However, there are questions to be clarified.
Method: Cross-sectional study approved by research ethics committee (70479517.2.0000.5020). The convenience sample consisted of 38 independent un hospitalized elderly recruited from two centers for the care of the elderly in Manaus, Amazonas, Brazil: 19 with PD and undergoing treatment with Levodopa (PG) and 19 controls matched by gender, age, and body mass index (CG). Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) in cmH2O; dysphagia risk by Eating Assessment Tool (EAT 10) questionnaire and vocal behavior by MPT (sustained fricatives/s, z and s/z ratio in seconds). Tests: Shapiro-Wilk, t-student, Mann-Whitney and Pearson’s Correlation Coefficient, significance 5%.
Results: The participants were asymptomatic regarding respiratory complaints. However, in PG 100% had vocal complaints and 59% presented some type of complaint regarding swallowing. MIP CG -66,1 ± 23,5 PG -43,3 ± 28,4 (P=0,011 t-student) and MEP CG +77,1 ± 20,8 PG +53,4 ± 32,7 (P=0,012 t-student). MPT/s CG 15,4 ± 3,9 PG 7,9 ± 3,9 (p<0,001 t-student). MPT/z CG 17,1 ± 4,2 PG 8,4 ± 2,8 (p<0,001 t-student). s/z ratio (IIQ) CG 0,9 ± 0,2 PG 0,9 ± 0,3 (p=0,95 Mann-Whitney). EAT 10 (IIQ) CG 0 ± 0 PG 14 ± 26 (p<0,001 Mann-Whitney). MEP was strongly and negatively correlated with the risk of dysphagia (p<0.05 Pearson Correlation).
Conclusion: There was a higher risk of dysphagia, RMS lower and strongly correlated with the risk of dysphagia.
References: KALF, J. G. et al. Prevalence of oropharyngeal dysphagia in Parkinson’s disease: a meta-analysis. Parkinsonism & related disorders, v. 18, n. 4, p. 311-5, 2012. CEREDA, E. et al. Swallowing disturbances in Parkinson’s disease: a multivariate analysis of contributing factors. Parkinsonism & Related Disorders, v. 20, n. 12, p. 1382-7, 2014. ARGOLO, N. et al. Swallowing disorders in Parkinson’s disease: impact of lingual pumping. International Journal of Language & Communication Disorders, v. 50, n. 5, p. 659-64, 2015. LUCHESI, K. F.; KITAMURA, S.; MOURÃO, L. F. Dysphagia progression and swallowing management in Parkinson’s disease: an observational study. Brazilian Journal of Otorhinolaryngology, v. 81, n. 1, p. 24-30, 2015. SU, A. et al. Clinical and manometric characteristics of patients with Parkinson’s disease and esophageal symptoms. Diseases of the Esophagus, v. 30, n. 4, p. 1-6, 2017. PFLUG, C. et al. Critical dysphagia is common in parkinson disease and occurs even in early stages: A prospective cohort study. Dysphagia, v. 33, n. 1, p. 41-50, 2018.
To cite this abstract in AMA style:
R. Gonçalves, T. de Freitas, N. de Souza, J. Veras, J. Barbosa Neto, C. Araújo, C. Do Amaral, D. Dalles, L. Cardoso, P. Cortez, E. Andrade, M. Cardoso. Dysphagia risk, respiratory muscle strength and maximal phonation time in elderly with Parkinson Disease in the initial stages [abstract]. Mov Disord. 2021; 36 (suppl 1). https://www.mdsabstracts.org/abstract/dysphagia-risk-respiratory-muscle-strength-and-maximal-phonation-time-in-elderly-with-parkinson-disease-in-the-initial-stages/. Accessed June 15, 2025.« Back to MDS Virtual Congress 2021
MDS Abstracts - https://www.mdsabstracts.org/abstract/dysphagia-risk-respiratory-muscle-strength-and-maximal-phonation-time-in-elderly-with-parkinson-disease-in-the-initial-stages/