Session Time: 1:45pm-3:15pm
Location: Agora 3 West, Level 3
Objective: 1. Is there a correlation between the concentration of hemoglobin in the blood and the development of Parkinson’s disease? 2. Does the high level of hemoglobin in the elderly age increase the severity of the course of already developed Parkinson’s disease?
Background: Despite the fact that hemoglobin is considered the most widely distributed source of peripheral iron in the body, the link between hemoglobin levels in the blood and the development of Parkinson’s disease is still not well understood. This report will address issues of iron aiding in brain neurodegeneration. There is also a link between the level of hemoglobin in the blood of old age in the population of Uzbekistan and the severity of Parkinson’s disease.
Method: We observed medical records from the TMA clinic Neurology department, for the period 2011–2018, medical records in the amount of 546 patients with Parkinson’s disease were examined, of which 312 cases (57.14%) were women in the age group 57–75 and 234 cases ( 42.86%) were men in the age group 61-83 years. General blood tests were analyzed to detect hemoglobin levels, and their results were compared with data from healthy people of the relevant age group.
Results: The amount of hemoglobin decreased significantly with age. In the age group 61–75 years old, 16.7% had a hemoglobin level of <14 g / dL versus 34% in the age group 75–86 years (p <0.001). During data collection, it was found that a high level of hemoglobin in the age groups and the severity of Parkinson's disease had a directly proportional upward trend. That is, a more severe course of the disease was observed in people with high levels of hemoglobin. The results of these patients were compared to the level of hemoglobin in the healthy group, where the level of hemoglobin was 24.1% lower than in patients with Parkinson's disease.
Conclusion: Although hemoglobin levels decline with age, evidence suggests that hemoglobin levels, which remain high in older people, are associated with an increased risk of developing Parkinson’s disease and the severity of its course.
To cite this abstract in AMA style:SH. Shohimardonov, K. Daminova. Examining level of hemoglobin in patients with parkinson’s disease and the role of hemoglobin level in the disease course [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/examining-level-of-hemoglobin-in-patients-with-parkinsons-disease-and-the-role-of-hemoglobin-level-in-the-disease-course/. Accessed December 7, 2023.
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MDS Abstracts - https://www.mdsabstracts.org/abstract/examining-level-of-hemoglobin-in-patients-with-parkinsons-disease-and-the-role-of-hemoglobin-level-in-the-disease-course/